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sebwalsh.bsky.social
Public Heath Doctor/Researcher interested in Dementia. PhD student at Cambridge. Scouser abroad (down South). Views own.
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Are you interested in policy action to reduce population dementia risk? A reminder to join us online for these three, free expert talks and Q&A starting at: NZ = 27th Feb 9am UK = 26th Feb 8pm EST = 26th Feb 3pm www.eventbrite.com/e/public-lec...

7 year follow-up from SPRINT trial: intensive vs standard blood pressure treatment for 3 years in high-CVD risk people resulted in a lower risk of MCI and cognitive impairment ?Underpowered for probable dementia as a solo outcome measure www.neurology.org/doi/10.1212/...

Population-level interventions like salt reduction programmes have an important role in protecting our 🧠 as we age, by reducing stroke and dementia risk from hypertension. And if done gradually, people don't notice the difference in taste! jamanetwork.com/journals/jam...

At some point we have to ask whether these sports, in which the aim is to punch someone else in the head enough times that they are no longer conscious, can continue to exist despite so much evidence that it can kill, and increase risk of dementia www.bbc.co.uk/sport/boxing...

Various re-hashings of v small treatment effects of AD MABs to persuade regulators of meaningfulness My heuristic: if it's debatable, it's probably not meaningful. If asserted through post-hoc re-framing, it's almost certainly not meaningful! alz-journals.onlinelibrary.wiley.com/doi/10.1002/...

No ⬇️ in dementia incidence across MAPT and preDIVA trials despite some risk factor improvements We won't make big (any?) dents in dementia incidence, a complex syndrome for which risk develops across lifecourse, through individual lifestyle interventions. Must think bigger! doi.org/10.1002/alz....

More recent generations of older people are reaching old age with greater intrinsic capacity (in better knick). Something to be celebrated. But we also need to work out how to maintain these trends, and reduce inequalities within them, moving forwards www.nature.com/articles/s43...

So excited for this event on Population-Level Approaches to Dementia Risk Reduction (PLADRR) in Feb. Hybrid talks from Carol Brayne, me, and Etu Ma'u. Free! Link below! Join us! 🇳🇿 27th Feb 9:00 🇬🇧 26th Feb 20:00 🗽 26th Feb 15:00 www.eventbrite.com/e/public-lec... www.eventbrite.com/e/public-lec...

Very significant study in Nature Medicine from the ARIC study team 42% lifetime risk of dementia at age 55. Higher than previous estimates, which they attribute to better ascertainment + more diverse sample Median age of dementia 81, sex difs show only after 85 www.nature.com/articles/s41...

Comparison of PAFs, PIFs, and national and subnational population-level policies, for dementia risk reduction in 🇮🇹. A tour de force of a paper from Simone Salemme and colleagues www.sciencedirect.com/science/arti...

We need to more in the dementia field to integrate into the broader NCD prevention agenda. And the NCD prevention agenda needs to do more to be inclusive of late-life diseases Dementia is a neglected noncommunicable disease and leading cause of death doi.org/10.1038/s415...

Objectively this would be very, very funny. If only the harm she caused when she *did* crash the economy wasn't so real www.bbc.co.uk/news/article...

Text message reminders with or without nudges, with or without chatbots, had no effect on adherence to chronic CVD meds. Nice trial showing that simple answers to complex problems don't work! jamanetwork.com/journals/jam...

The commentary from Levy on the limitations of the NIH meta-analysis of fluoride and children’s IQ really is quite striking and worth reading for any #publichealth folk

Here’s hoping 🤞

🧠Diagnosing Dementia🧠 How do we diagnose dementia? 🌟 Huge thanks to the Alzheimer's Research UK Inspire Fund for funding this video. #DementiaAwareness #ResearchMatters Watch below: ➡️➡️➡️ www.youtube.com/watch?v=982J...

A lot of rich parents are very upset at the government for charging VAT on private school fees. Maybe they should instead ask why private schools have put up fees so far above inflation over the past 15 years. www.ft.com/content/852b...

👇

What to do about towns in England? A very thoughtful longer read blog from Tim Leunig open.substack.com/pub/timleuni...

A scathing indictment of the proposed new Alzheimer's diagnostic criteria: www.thehastingscenter.org/dont-give-sy.... When pharma talks about big effects of their drugs on biomarkers, they are trying to distract from what they did NOT see: big effects on symptoms, enduring improvements in QoL.

Gd news that councils will receive ⬆️funding to help towards employer national insurance contributions (NICs), but like the LGA, we worry about the impact the NICs⬆️ will have on the charities and providers our members rely on to deliver vital public health services. www.local.gov.uk/about/news/l...

Unpicking causal relationship between hearing loss and dementia is complex. Good paper showing some of this in UKBB via target trial emulation design, albeit with imperfect data. Residual confounding, inequalities in healthcare access important factors to consider academic.oup.com/aje/advance-...

Impressive attempt to consider sex differences in dementia not just as a biological construct, but a social one: Early life exposure to structural sexism and late‐life memory trajectories among black and white women and men in the United States alz-journals.onlinelibrary.wiley.com/doi/10.1002/...

Is 'Precision Public Health' an oxymoron? A poster I prepared for the recent @cph.bsky.social 2024 showcase event cph.shorthandstories.com/poster-showc...

Elvis getting his polio vaccination backstage on The Ed Sullivan Show, 1956, which aided the nationwide vaccine campaign.

Fantastic resource - 15 booklets with practical advice for those caring for a loved one with #dementia, from continence and dressing to emotions and finances. Worth sharing! @nihr.bsky.social funded research led by Worcester University caringhelp.on.worc.ac.uk

Transport is vital for living a healthy life. This new paper shows improving public transport is central to health equity by promoting active travel to work and reducing emissions. www.instituteofhealthequity.org/resources-re...

My friends in the Dementia world. Please read this and consider what the effects on healthcare for people with Alzheimer’s disease in England would have been if NICE had approved lecanemab and donanemab for NHS use. And, of course, they don’t have clinical efficacy, anyway!

Amazing paper in @thelancet.bsky.social evidencing something we argue in #publichealth the whole time: the opportunity cost of increasingly expensive medications 'During 2000–20, NHS coverage of new drugs displaced more population health than it generated.' www.thelancet.com/journals/lan...

Lost access to my Mendeley library (9.5k references) this morning - totally my fault and complicated to resolve. Big thanks to @elsevierconnect.bsky.social who resolved for me (free help to fix a free programme) 🙌

doi.org/10.1136/bmj-... How to maintain trustworthiness when doctors act as policy advocates Re-sharing this thread for Bluesky followers, from our @bmj.com long read piece back in August. Still feels very timely 1/

Scientists, academics, researchers: We’re excited to share that @altmetric.com is now tracking mentions of your research on Bluesky! 🧪

Given the exodus of academics from X to BlueSky, isn't it time that journal websites added a 'share to bluesky' option?

Well conducted cohort study in EPIC-Norfolk reporting increased dementia risk for mid-life/early late-life metabolic syndrome www.thelancet.com/journals/lan...

Cannot move for peer review requests - do journals get a spike in submissions at the end of the year? If so, are acceptance rates (or at least turnaround times) higher if you submit in earlier months of the year? Asking the important questions, one at a time 😆