sethlucianmasters.bsky.social
Professor and Head of the Centre for Innate Immunity and Infectious Disease at the Hudson Institute.
11 posts
1,274 followers
375 following
Getting Started
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Amazing work by first author @shouyafeng.bsky.social with the support of @hudsonresearch.bsky.social and many others!!!
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We tested this library of NLRP3 variants in response to stimulation, at low temperature (some patients with CAPS have temperature sensitive flares), and in response to a NLRP3 inhibitor, all of which yielded interesting results. If you have another idea, we are happy to share the library with you!
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Data available through
infevers.umai-montpellier.fr
and
www.geniadb.net/app/gene/inf...
any variants we did not test yet please let me know!
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My apologies, it looks like this meeting is not being broadcast. Depending on what you are interested to hear about, there could be some recordings or other resources I can point you towards.
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A really important consideration in the study of #autoinflammatory and other primary immune diseases. Extremely interesting findings @bogunoviclab.bsky.social !