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srijitseal.com
Senior Chemøinformatics at Merck | Postdoc@Broad Institute of MIT and Harvard, Cambridge(MA) | PhD@University of Cambridge(UK) | AI, Image Analysis, bioML, -omics data, and Cell Painting for drug discovery. srijitseal.com/tools
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Excited to join Merck US as a Senior Research Scientist! If you are in Philly area, would be happy to catchup!

Machine Learning in Drug Discovery Resources page updated for 2025. github.com/PatWalters/r...

pip install infoalign! Add biological information to your chemcial fingerprints, using only SMILES as input! I'm thrilled to share that our paper "Learning Molecular Representation in a Cell" has been accepted to ICLR 2025! 🎉

Thou shalt not promise lower grocery prices and then deliver war against Panama, Canada, and Greenland.

Open #postdoc position in *Organic/Medicinal Chemistry* for generative #AI in Drug Discovery — join us @tueindhoven.bsky.social 💪🏻 Funded by the European Research Council (ERC). Deadline: Jan 15, 25 jobs.tue.nl/nl/vacature/... Repost appreciated!

“Your scientists were so preoccupied with whether or not they could, they didn't stop to think if they should”

I don't think it's widely clear to the #RadiologyAI community just how poorly GPT-4V compares with the top report generation models on chest X-rays, like MedVersa or MAIRA-2. It's clear we need a way to track progress.

Atomic orbitals at the beach #chemsky 🧪

The next Cambridge Cheminformatics Newsletter, December 2024 Edition is out! Containing upcoming related events, news jobs and resources For details please see: www.drugdiscovery.net/2024/12/22/c... Have a good Christmas/Holiday period everyone! All the best and see you in 2025, Andreas

Here's a Cheminformatics Starter pack! Let me know if you would like to be added! And more importantly, do encourage people to join the blue skies :D

I did the experiment myself! Having an Android phone saves you 25% costs and the phone pays for itself in 10 Uber rides! Uber and other apps cost up to 30% more on iPhones than on Androids for the same orders. Don’t get me wrong, by all means buy an iPhone! Keep an Android on the side for orders 🤪

🎉 I'm starting my own lab at EMBL-EBI (Cambridge, UK; June 2025) 🎉 We will focus on identifying and characterizing chemical hazards to humans and ecosystems using computational biology methods. I am beginning the search for two postdocs now - stay tuned for more details! ewaldlab.org

New Year, new job? Delighted to announce two early-career-level (post-BA/BS or MA) positions in my lab, and an open call for computational postdocs at the Broad! First, an image analysis associate - work on high content screens for all kinds of cells and dimensionalities! See more at link (1/4)

We've a postdoc opening for our lab at the Broad: Cambridge MA! Must have experience in toxicology + data science Work on the wonderful OASIS dataset we are producing... Cell Painting, transcriptomics, proteomics in various liver cell and tissue models! broad.io/mlcbpostdoc

Pack 3 now up to 69/150!

It’s not that large is it… hmm

Note: most MIT professors I know are honest and morally upright

Postdoctoral Opportunity!

Thinking about implementing the Cell Painting assay? Here’s a guide to how it can help in Drug Discovery! t.co/hW1jOhAg7q

My (I think funny) take on AlphaFold3 and equivariance: There are many versions of AF3 which may be better at different tasks — The one they publicly released is as diametrically opposite in terms of architecture (no equivariance, no frames, generative) to RosettaFold-AllAtom.

212e, I won’t miss you! Not at all!

Due to recent events and such...

When the size of test data is 5 compounds and accuracy is 100% 😌

We’re thrilled to share our Nature Methods review on #CellPainting — your go-to resource for mastering Cell Painting! From MOA and toxicity prediction to contributing to candidate drugs in clinical trials, we’ve distilled 10 years of insights!

The JUMP-Cell Painting findings with genetic perturbations are now released!

Scientists, academics, researchers: We’re excited to share that @altmetric.com is now tracking mentions of your research on Bluesky! 🧪

ICLR ACs - save us!

Calling all systems and computational biologists in search of a faculty position: We have Assistant and Associate Professor positions! 🚀 Pittsburgh is beautiful, and we are doing amazing science here. cfopitt.taleo.net/careersectio... cfopitt.taleo.net/careersectio... Please apply by Dec 2!