stjuderesearch.bsky.social - Profile | ThreadSky | a Reddit-style client for Bluesky

Congratulations to Senthil Bhoopalan, MD, PhD, for earning the American Society of Pediatric Hematology/Oncology (ASPHO) Young Investigator Award for his work in preclinical development of genome editing for Diamond-Blackfan anemia syndrome.

submitted 3 days ago • 0 comments

We’re excited to announce Hongbo Chi, PhD, as the new Chair of the St. Jude Department of Immunology. His leadership will advance our mission to find cures for catastrophic childhood diseases.

submitted 3 days ago • 1 comment

Richard S. Finkel, MD, director of the Center for Experimental Neurotherapeutics at St. Jude Children’s Research Hospital, has been named to TIME100 Health, recognizing his contributions to global health in 2025.

submitted 4 days ago • 1 comment

What a great way to kick off the morning with ASPHO Keynote #HayleyArceneaux of @stjuderesearch.bsky.social ! Nothing like a little inspiration with your morning coffee. #PHODocs #PedsHemeOnc #MedSky #MedEd #PedsSky #HemeSky

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Scientists developed a patient-derived organoid model for UBA5-associated encephalopathy, revealing stunted GABAergic interneuron growth as a cause of seizures. Boosting activity of the hypomorphic UBA5 gene shows promise as a potential therapy.

submitted 5 days ago • 1 comment

Science thrives on collaboration. Postdoc Maowei Hu, PhD, was the first author of a Nature paper for which she developed a barcoding system that analyzes thousands of chemical reactions — a breakthrough accelerating drug discovery.

submitted 7 days ago • 1 comment

For over 60 years, St. Jude has pioneered new understanding and treatment for catastrophic pediatric disease. These innovations have helped transform sickle cell disease, leukemia therapies, HIV care, radiation oncology and cancer genomics.

submitted 11 days ago • 1 comment

Vaccination is critical for immunocompromised patients recovering from chemotherapy or bone marrow transplantation. Octavio Ramilo, MD, St. Jude Department of Infectious Diseases chair, is leading research to improve vaccine efficacy and immune recovery in these vulnerable populations.

submitted 12 days ago • 1 comment

Congratulations to Charles Mullighan, MBBS, MSc, MD, for receiving the @theaacr.bsky.social-St. Baldrick's Foundation Award for Outstanding Achievement in Pediatric Cancer Research. Your commitment to groundbreaking research in ALL is inspiring. #AACR25

submitted 13 days ago • 0 comments

Tiffany Eulalio, PhD, is a postdoc in epidemiology and cancer control at St. Jude Children’s Research Hospital. She presented her research on Precision Medicine in Pediatric Cancer at #AACR25, focusing on improving health outcomes for childhood cancer survivors.

submitted 13 days ago • 1 comment

Congratulations, Adam Durbin, MD, PhD, for being honored as an @theaacr.bsky.social NextGen Star. Thank you for your work translating laboratory discoveries into clinical breakthroughs for children with difficult-to-treat malignancies. #AACR25

submitted 15 days ago • 0 comments

Congratulations to Jinghui Zhang, PhD, for election to the 2025 class of Fellows of the @theaacr.bsky.social Academy. Your commitment to developing St. Jude Cloud and your computational expertise in pediatric cancer genomics continues to advance research. #AACR25

submitted 16 days ago • 0 comments

Congratulations to Charles Roberts, MD, PhD, for election to the @theaacr.bsky.social Board of Directors. Your commitment and leadership in the advancement of cures and preventions for cancer continues to drive progress. #AACR25

submitted 17 days ago • 1 comment

Our researchers, in collaboration with the Medical College of Wisconsin, have discovered how chemokines and G protein-coupled receptors (GPCRs) selectively bind to control how cells move. ow.ly/77Yl50VGpKe

submitted 19 days ago • 1 comment

Childhood cancer survival rates are below 30% in resource-limited countries, partly due to underdiagnosis and lack of reliable data. A new registry created by St. Jude Global Scholar Venkatraman Radhakrishnan, MD, is addressing this gap in Chennai, India.

submitted 20 days ago • 1 comment

The Global Platform for Access to Childhood Cancer Medicines unites the @who.int, @unicef.org, PAHO, health officials and patient advocacy groups to deliver life-saving medicines and strengthen health systems in resource-limited countries.

submitted 20 days ago • 1 comment

The Clinical Biomarkers Laboratory at St. Jude is advancing research by enabling investigators to use clinical trial data for additional discoveries. From custom immunoassays to liquid biopsies, the lab delivers faster, personalized and cost-effective findings. Learn more: ow.ly/FLku50VComP

submitted 25 days ago • 0 comments

Scientists uncovered new insights into FOXR2 activation in pediatric brain tumors, reshaping diagnostic and treatment approaches. FOXR2 was previously thought to occur only in CNS neuroblastoma. Using data from St. Jude Cloud, researchers found it activated in other tumor types. ow.ly/O6Mx50VBPav

submitted 26 days ago • 0 comments

Scientists developed new frameworks to selectively inhibit CYP3A4, a protein that breaks down a large number of FDA approved drugs, reducing their efficacy. This research identifies a new way to block CYP activity without the off-target effects of traditional inhibitors. ow.ly/RKcL50VyVr4

submitted 31 days ago • 1 comment

Childhood cancer survivors face reduced bone density, much like astronauts returning from space. Sedentary behavior during treatment and therapy-related impacts on bone health create long-term challenges.

submitted 34 days ago • 1 comment

Scientists have advanced our understanding of chromatin remodeling by using cryo-EM to capture the enzyme SNF2H at 13 distinct stages of nucleosome sliding. These findings provide a detailed view of how chromatin remodelers regulate DNA access. Read more: ow.ly/mhv150VtUoH

submitted 39 days ago • 0 comments

M. Madan Babu, PhD, Chief Data Scientist at St. Jude Children's Research Hospital, has been inducted into the @aimbe-official.bsky.social College of Fellows Class of 2025. AIMBE honors the top 2% of medical and biological engineers globally.

submitted 41 days ago • 1 comment

A new study showing decreased survival rates among pediatric cancer patients in conflict-regions highlights a need for novel multidisciplinary interventions to confront the challenges associated with political instability and violent conflict. Read more: ow.ly/qNpp50VrZmf

submitted 41 days ago • 0 comments

High-performance computing (HPC) is transforming biomedical research at St. Jude. The HPC cluster allows researchers to process massive datasets in hours instead of weeks, enabling breakthroughs in neuroblastoma drug combinations, genomic cancer risk analysis and CAR T-cell immunotherapy design.

submitted 45 days ago • 1 comment

The St. Jude Center for Proteomics and Metabolomics is advancing our understanding of biology and disease by analyzing proteins and metabolites. Using cutting-edge mass spectrometry, the Center identifies more than 10,000 proteins and thousands of metabolites in a single experiment.

submitted 49 days ago • 2 comments