uvmtraumalab.bsky.social
Can we resuscitate damaged endothelium after injury? | Physician-scientist studying small blood vessels and trauma physiology at the University of Vermont 🚑 | Father, dog-lover, snow-sport enthusiast, and bluegrass fiddle player 🎻
130 posts
798 followers
2,362 following
Prolific Poster
Conversation Starter
comment in response to
post
The DOGE chainsaw just hit a huge spike!
Emergency ruling by federal judge in California has temporarily shut down the illegal overhaul of the federal government, including attacks on NIH and NSF.
comment in response to
post
Congrats to postdoc Grace Bonson & team! And thanks to our sponsors and the Shock society for both the trainee award at the Annual Conference on Shock and the opportunity to publish in @shockjournal.bsky.social. This was made possible by funding from #NIH #NIGMS #NHLBI.
#UVM #UVMLarnerMed
5/n
comment in response to
post
Histone levels are increased in the blood in #trauma and #sepsis. We found that blocking the scramblase TMEM16f prevented pro-thrombotic activation of endothelial cell plasma membranes caused by histone exposure. Could this be a therapeutic target?
#ImmunoSky #EMSky #Medsky #Scicomm
4/n
comment in response to
post
TMEM16f is also an #ionchannel. Blocking it prevented endothelial cell calcium release produced by histone exposure.
3/n
comment in response to
post
Scott’s syndrome is considered a #platelet disease caused by defects in TMEM16f, but knocking this out in platelets does not cause bleeding problems. In contrast, we found that knocking out TMEM16f in #vascular endothelial cells prevents normal #bloodclotting.
2/n
#Immunosky #EMSky #Medsky 🧪
comment in response to
post
Congrats!!! Well deserved.
comment in response to
post
“If the goal were to identify and address problems at these agencies in a good-faith manner, that would be one thing. But what is going on is akin to performing open-heart surgery on a patient who is not particularly sick using a blunt axe.”
2/2
comment in response to
post
Fake news
comment in response to
post
LOL! It’s like musical chairs, move people from the waiting room into the ER and then back out to optimize use of space. I guess it could work!
comment in response to
post
That’s a step backwards. Evidence supports moving patients out of the ER to board in the hallways or waiting areas of their admission unit, closer to the providers who can best care for them.
comment in response to
post
Thanks to #FASEB and #ASBMB for fighting for #science! FASEB’s Capitol Hill day was a well-coordinated effort to advocate for science and provide important information about #NIH and #NSF to our representatives in Congress.
#FASEBonTheHill #FundScience #NIH #MedSky #AcademicSky #UVMLarnerMed🧪
comment in response to
post
Go Buffs!!
comment in response to
post
Yes Yale SOM, here is their announcement yaledailynews.com/blog/2025/02...
comment in response to
post
The University of Arizona set up a fund for this too: tucson.com/news/local/e...
comment in response to
post
Go Blue!