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yeastlife.bsky.social
Biology Prof at William & Mary | SUMO in stress tolerance and protein quality control | lab life | yeast genetics | undergraduate research | backyard nature | opinions my own https://sites.google.com/view/yeastgenetics/home
81 posts 312 followers 447 following
Prolific Poster

Download it while you can - Useful, original and FREE online Introduction to Genetics Textbook! Support for this includes the Department of Education and it is based upon work supported by the National Science Foundation. bio.libretexts.org/Courses/City...

Do you know Daisy Roulland-Dussoix? She is one of the discoverers of restriction enzymes, who’s findings paved the way for the development of recombinant DNA and cloning technologies. Accordingly, the finding was rewarded with a #NobelPrize. But the prize didn’t go to her. 🧵👇

🚨🚨🚨

If any crystallographer has wondered what it feels like to be inside a crystal, I would recommend the Yayoi Kusama exhibition 🤩💎

A little known place on W&M campus - overgrown abandoned amphitheater from 1957 scrc-kb.libraries.wm.edu/cove-amphith...

Instant Stress relief in the time of science denialism

William & Mary, VA sunken gardens in the snow

Scientific advancements aside, this is economically irresponsible Every $1 spent by NIH generates $2.46 For example, in 2023, $47B in NIH spending generated ~$93B Halting NIH spending will LOSE the US a lot of money (and talent)

Happy MLK Day: ... King went on, “because the world is all messed up. The nation is sick. Trouble is in the land; confusion all around…. But I know, somehow, that only when it is dark enough, can you see the stars.” open.substack.com/pub/heatherc...

Relevant to this audience! @nature.com asks: “Has Bluesky replaced X for scientists? Take Nature’s poll”: www.nature.com/articles/d41... 🧪

📣 SAVE THE DATE: EMBO workshop SUMOylation: from discovery to translation. 22-25 Sept 2025. La Grande Motte (France) Registrations will open soon: coming-soon.embo.org/w25-59

Rinehart, L., Stewart, W. E., Luffman, N., Wawersik, M., Kerscher, O. (2024). Chigno/CG11180 and SUMO are Chinmo-interacting proteins with a role in #Drosophila testes somatic support cells. PeerJ, 12:e16971 peerj.com/articles/169...

Props to the parasitologist who not only pulled a parasitic nematode from his own mouth and published a paper on it, but also named it "Buddy" and then staged a re-enactment of its extraction with his co-author, using a gummy worm www.wm.edu/news/stories...

of course I ran out seeds for the first real snow and the birds giving me the stink eye

Frozen paws 🐾❄️ ain’t stopping this li‘l guy on our snow dog walk.

Another snow day!

Over 60 German universities and research institutions announced their departure from X today.

back in #Asheville, NC and Ginger’s Revenge brewery for their delicious ginger brews! The French Broad river front is still devastated after Hurricane Helene - major clean up ongoing. Asheville is making strides recovering and locals working very hard to get their city back. #AshevilleStrong

Office power-naps are so underrated!

I just love these phenotype-based drosophila gene names! This one is a perfect example!

"Because of the projector this slide looks different on my computer, you'll have to trust me that there's an effect"

Fact checking is not censorship. It's an essential public service. Disinformation kills. Period.

ULP-2 is a conserved SUMO protease required for embryonic development in #Celegans, but what does it do? This study shows that ULP-2 controls germline development by regulating #SUMOylation levels (and so activity) of H3K4me3 reader SET-26 🧪 @plosbiology.org plos.io/403ixQ5

Ok - but 64% is still D-

Towards community-driven visual proteomics! Excited to finally share this large-scale curated & annotated dataset of 1829 high-quality #cryoET tomograms of the little green alga that just keeps giving— Chlamydomonas! 🧪🧶🧬🌾🌊🌍 Preprint📜: www.biorxiv.org/content/10.1... A short thread🧵👇

Ready for our 0.02 inches of snow ❄️ in Williamsburg, VA! Bring it on! #snow #snowmageddon

Interested in #TPD? This might be for you. What concentrations of UPS inhibitors are safe to use to prove your proteasome dependent degradation mechanism? #PROTAC #TPD #degradation #Science #drugdiscovery pubs.acs.org/doi/10.1021/...

Asleep or awake - Lucy and Bode wish all a Happy New Year! #gooddog

Koa is a senior #CanineCompanions service #dog enjoying his retirement! #gooddog #goodboy

“unlicensed use of creative works for training generative AI is a major, unjust threat to the livelihoods of the people behind those works, and must not be permitted”. Sign this statement and make sure that our voices are heard. www.aitrainingstatement.org

Are you or your undergraduate trainees looking for a summer research internship in neuroscience? Consider the @fralinbiomed.bsky.social NeuroSURF program! More info: fbri.vtc.vt.edu/education/un...

Saw this proud tree-hole owner squirrel on our morning dog walk #sqrlpix

Wishing all my science friends a restful holiday, uninterrupted by freezer temperature alerts from their labs 🥶 🥵

Episode IV – A New Hope: arrived at the lab today to find that the construction crews working nearby had (without any notice) completely closed off our entrance. Thankfully, this was found to be an “unplanned error” and has since been corrected.

Lucy #pup wearing her #christmas finest! Happy holidays!

4. Advent!

Fighting to avoid her mother's fate, for her daughters sake - an important and timeley NYT story on frontotemporal dementia diagnosis, research, and hope by Virginia Hughes #FTD, #NeurodegenerateDiseases, #tau: www.nytimes.com/2024/12/22/h...

Maybe they are trying out a new Ai that provides a more cost-effective solution for proof editing! #aihallucination #science 🧪

just blurted out in class "yes, you have to cite where you got your info. in a world in which lying loudly is the only thing that seems to get rewarded, citing your sources is an act of resistance" and folks, I really believe that.

Awesome!

The legend @vyleart.bsky.social is here - do yourself a favor and go give him a follow!! If you’re a fan of #avatar, he’s recently been dropping some early Way of Water concepts that are just spectacular!

We are now looking for three more researchers to join us as #FocalPlaneCorrespondents in 2025. If you are interested in getting some #scicomm experience alongside your research, check out our post and drop us an email if you have any questions. focalplane.biologists.com/2024/12/17/b...