Profile avatar
brucelab.bsky.social
#NewPI in #RNA #Virology, electron microscopy aficionado, gardener, parent, Assistant Professor @UVMLarnerMed. Prev @Gates_Cambridge scholar
129 posts 1,577 followers 509 following
Prolific Poster
Conversation Starter

Yesterday, the NIH R35 “Outstanding Investigator” grant to fund scientists in my lab studying antibiotic resistance was terminated for reasons not related to the content of the science, or any actions taken by me or members of my lab

How can a Salmonella effector change the specificity of a host kinase? SteE mediates kinase reprogramming via mimicry of conserved eukaryotic-like motifs- doi.org/10.1038/s443... Great collaboration with @katrinrittinger.bsky.social + big thanks to all authors & congrats to lead PDRA Ioanna Panagi!

SaveNSF is a coalition of concerned scientists and allies who are working to save funding for scientific grants through the NSF. The mission is to support and advocate for the continuation of vital research and innovation. Join: www.savensf.com

Exciting news! We have two postdoc positions opened in our lab @UF! Study gut hypoxia & virus immunity OR immunity and intracellular trafficking in polarized cells. Come do cool science with a fun team! Check out all details: boulantlab.com/opportunities #PostdocJobs #ScienceTwitter

NEW: NIH has turned off researchers' ability to request 'no-cost extensions', which extends their funding without requesting extra money. Now they'll be manually approved by NIH staff. This is to ensure the "activities proposed during the extension align with the NIH mission and agency priorities"

Exciting job opportunities! Two postdoc positions are available in the Fodor Lab at @dunnschool.bsky.social to study influenza virus transcription, genome replication, nuclear export and assembly. More info: my.corehr.com/pls/uoxrecru...

The American Society for Microbiology is committed to ensuring that scientific research is conducted adhering to strict standards for biosafety and biosecurity, but pausing research is not the path forward. Read our statement: asm.org/press-releas...

virologists knew this was coming; this order is full of vague language that is more likely to slow down important research than provide greater biosafety and biosecurity. There was a framework that was supposed to be initiated today - but now we start from scratch www.whitehouse.gov/presidential...

On Friday, my son stayed home from school because he had a sore throat and wasn’t feeling well. He went with my husband to his office for the morning while I handled our daughter. When he came back at lunch, he was not interested in eating, saying his throat hurt too much. 1/n

Paging Sen Cassidy.

Staff members at the US National Science Foundation (NSF) were told on 30 April to “stop awarding all funding actions until further notice,” according to an email seen by Nature. https://go.nature.com/44Ugf9V

New NIH Guide Notice about foreign subawards grants.nih.gov/grants/guide...

RFK Jr. ordered the NIH’s Integrated Research Facility in Frederick to stop all research on serious infectious diseases yesterday at 5:00 PM. They study pathogens like Ebola there. You may be familiar with it from The Hot Zone. www.wired.com/story/hhs-ni...

NEW: An NIH policy coming in the next week will target — and at least temporarily stop — funding outside the US, threatening thousands of projects and collaborations on topics like infectious diseases and cancer. Some NIH staff have already been told to hold all subaward funds for foreign labs.

NIAID's Integrated Research Facility is one of the few federal facilities charged with studying Ebola. Tuesday afternoon, all of its work was put on indefinite pause by Robert F. Kennedy Jr.'s department. www.wired.com/story/hhs-ni...

This is essential. The gears that need to turn to produce NOAs have been ground to a halt, while grants have been terminated rapidly and without process. The intent here is clear. #StandUpForScience

Non-spike protein mutations in #SARSCoV2, likely to impact viral properties, are understudied. @brucelab.bsky.social show that a #nucleocapsid protein mutation in Delta variant enhances viral growth in vitro & in vivo by increasing viral genome #encapsidation @plosbiology.org 🧪 plos.io/4iBYsaI

For US students interested in the UK, if you have an acceptance letter from a US college or university, these applications will be considered rapidly at @exeter.ac.uk for the 2025/2026 year. If you're interested in an MSc or PhD, happy to chat & support. I study #Drosophila #Immunity #Genetics 🪰🦠🧬

Thrilled to share that our latest manuscript using smFRET to study inhibition of SARS-CoV-2 is now out! doi.org/10.1093/nar/... Congrats and thanks to amazing co-authors and collaborators for all the hard work. @efodor.bsky.social @jeremykeown.bsky.social @andrewmcmahon1345.bsky.social

Non-spike protein mutations in #SARSCoV2, likely to impact viral properties, are understudied. @brucelab.bsky.social show that a #nucleocapsid protein mutation in Delta variant enhances viral growth in vitro & in vivo by increasing viral genome #encapsidation @plosbiology.org 🧪 plos.io/4iBYsaI

Very happy that this story is now published in @plosbiology.org. It includes lots of additional data, (creation of the G215S mutant) & demonstrates the increased growth/ oligomerization of N is specific to the cysteine at 215. Thanks to the coauthors, reviewers and editors who helped improve it!

"The core strategy is to slow NIH spending to generate surpluses...then use surpluses as justification for slashing the budget...unspent [$] won’t be because NIH doesn’t have good science to spend on [but] because the administration has blocked spending" donmoynihan.substack.com/p/the-nih-bu...

Terry Dermody and I wrote an op-ed about chronic diseases ("Make America Healthy Again"), the role of viral infections, and how virologists can help. www.post-gazette.com/opinion/gues...

Here is the link to the Last Week Tonight with John Oliver about RFK, Jr, public health, and HHS (including NIH) www.youtube.com/watch?v=8H34...

🚨 This MUST READ essay and call to action spells out, in very clear terms, how the Trump administration could get away with slashing the NIH budget. NIH scientists and Dems in congress need to read and understand it. This is where we win or lose the battle to save the NIH and US science. 🧪 🧠 🧬 🔊

Except DEI, of course. Talking about the benefits of diversity and equity risks having your NIH grant pulled so keep your trap shut. www.nih.gov/about-nih/wh...

I'm very excited to share the latest work from my group, led by @ahturner934.bsky.social. We revisited one of my favorite proteins (Rab11) and its role in influenza infection& discovered surprising new things. Rab11B is required for entry of current H3N2 isolates! 1/n www.biorxiv.org/content/10.1...

Come join us at @mcgill.ca as an assistant professor in virus-host interactions! Please share widely. mcgill.wd3.myworkdayjobs.com/en-US/McGill...

Preprint from our lab is out! We identified a peroxisome-localized acyl-coA binding protein AcbdA - that regulates peroxisome movement. www.biorxiv.org/content/10.1.... Congratulations to members of my lab and the Christensen lab @christensenlab.bsky.social www.biorxiv.org/content/10.1...

New acting director at NIAID is familiar face to flu researchers. www.science.org/content/arti...

ATTENTION I am hearing from several sources that "NIH" sent out termination notices for most or all "diversity" awards yesterday to coincide with the new Notice. If you were affected by this and are willing to share, please DM me or reach me on Signal (jeremymberg.78) 1/2

Know any soon to graduate or recently graduated postbac researchers interested in / with experience working with phages? We are hiring a junior specialist/research tech! Apply here: aprecruit.berkeley.edu/JPF04863 (start date more flexible than stated in ad!)

Sorry to get political but I think we should pay people to check for poop in our food