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jcons.bsky.social
microbial ecology, metagenomics, science policy and funding. Ph.D. in systems & computational biology (2024)
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New Consensus Statement in Nature Microbiology! Working with low-biomass microbiome samples? From deep subsurface rocks to human lungs, contamination is a major challenge. We offer field-to-data analysis guidelines to help keep your results clean. 📖 doi.org/10.1038/s415...

🥁NEW publication from our lab: the largest meta-analysis of gut microbiome associations with CRC! www.nature.com/articles/s41... 🧵⬇️ 1/6

"This cross-sectional study of the oral microbiome in US adults showed that a few genera were universally present and a different set of genera explained a high percentage of oral microbiome diversity across the population."

The “brain drain” will be a primarily domestic phenomenon, w/ STEM-trained people moving into non-STEM occupations. There are not remotely enough STEM jobs abroad for our *millions* scientists, and even if there were, moving is hard, expensive & dependent on multiple intersecting privileges.

There are a lot of questions being asked about the awarding of a $500M grant to an #NIH team to develop a new (old) vaccine platform that could be used for a "universal" #flu vaccine. www.statnews.com/2025/05/03/n...

NSF has two kinds of grants, standard (where all of the awarded $ is issued up front) and continuing (where the awarded $ is issued in yearly increments). It sounds like they're freezing any expenditures on awarded continuing grants and not making any new awards for now. Disastrous for US science. 🧪

NEW: We (mostly @noamross.net) launched a website to shine a brighter light on terminated NIH and NSF grants. grant-watch.us It links to our NIH & NSF trackers, grant info submission forms, and other info. We'll also add new analyses soon. Check it out and let us know what else you'd like to see.

Our subclustering and transmission pipeline, PopPIPE has now been published: www.microbiologyresearch.org/content/jour...

I assumed someone had done this already- could be pretty cool for microbial ecology/defined community work www.nature.com/articles/s42...

Journalists need to stop letting non-experts say unchallenged how "great" LLMs are for researchers and scientists and actually talk to a few. The public has the conception that this tool is in use by mathematicians and scientists using it to craft theories, when it is totally useless for this

NIH announces Human Instrumentality Project www.nih.gov/news-events/...

www.nature.com/articles/s41...

ICYMI: New online! The global resistance problem and the clinical antibacterial pipeline

Now over a month since this beauty made it into print! journals.asm.org/doi/full/10....

I am thrilled to share the first manuscript from the Wiles lab! We present "Phollow", an in vivo phage-tagging approach that enables direct observation of phage outbreaks with single-virion resolution by live imaging. Here some highlights 👇 www.nature.com/articles/s41...

Ok so yeah, this has quickly become the #1 misunderstanding about the canceled grants the grants are not “subsidies” or “entitlements” to Harvard or Princeton or whatever they aren’t going into universities’ endowments they are competitive contracts won by these universities to do research

This is just unbelievable

In a review led by @gilbertjacka.bsky.social in @natmedicine.bsky.social we highlight the state of clinical translation in microbiome research. We have gone from basic discoveries to FDA-approved therapies in <20 years, on par with the pace of mRNA vaccine development. www.nature.com/articles/s41...

We found a really cool giant virus inside the genome of a green alga, and it has a very strange infection cycle that is hard to detect. There are reports going back decades of viral particles spontaneously appearing in pure cultures of green algae, so this phenomenon seems quite common but […]

WHAT www.nytimes.com/2025/04/09/b...

This is a big deal. Spread the word. But it’s tiny compared to the totality of what’s happening at NIH. Cure Research for all cancers, Alzheimer’s, everything is being gutted. Intentionally. It’s all getting burned to the ground but the news isn’t getting out. The new cures won’t be there for you.

When I was in grad school in the 90's the rule of thumb from twin studies was that the heritability of everything was ~50%. It turns out that twin studies are highly confounded, & after unconfounding w/ new genome-based methods (Family-GWAS), the median heritability of behavioral phenotypes is ~5% 🧪

Today I've gotten instagram ads looking to poach American talent from both Australia and Denmark

www.statnews.com/2025/04/04/o...

NOAA’s office of Oceanic Atmospheric Research has had IT and other support contracts canceled in the last day or so that will fundamentally affect its operation. One source there said “It will seriously hurt our ability to improve weather forecasting and climate projections.”

This is really, really bad. These are the most common individual fellowships for grad students and postdocs.

Just before bedtime last night I got a message from inside NIH which read: “It’s so, so bad and no one cares (who has any influence)” I asked “What, in particular?” My friend responded “Everything”

The concept of media literacy is now Woke

it's so cool how Grand Vizier Chat (secret) is not only real but in fact the preferred policymaking apparatus of the global hegemon

From 2010 to 2016 (latest data I have ), NIH research contributed to EVERY drug approved by the FDA

Reading some biotech news

Scientists have invented a new way to cook eggs www.nature.com/articles/s44...

The physical biogeography of Fusobacterium nucleatum in health and disease https://pubmed.ncbi.nlm.nih.gov/40062772/

its amazing how chatgpt knows everything about subjects I know nothing about, but is wrong like 40% of the time in things im an expert on. not going to think about this any further

I gave Claude the easy task of comparing two lists of genome accession numbers. The python script it wrote functions correctly, but the matches it lists below DO NOT EXIST. You need to be very careful with LLMs. Errors like this could derail an entire project!