roisinmcmanus.bsky.social - Profile | ThreadSky | a Reddit-style client for Bluesky

Can AI-designed binders degrade, aggregate, stain and enrich endogenous proteins in human cells? Check out our new preprint! www.biorxiv.org/content/10.1...

submitted 15 days ago • 1 comment

📢 We are #hiring a #PhD student to work on an interdisciplinary, collaborative project @dzne.science in Bonn, Germany! 🧠 If you’re interested in western diet-induced #neuroinflammation and innate immune signalling in #alzheimersdisease, check out our ad below 👇 jobs.dzne.de/en/jobs/1014...

submitted 18 days ago • 1 comment

Had a great time visiting @tcddublin.bsky.social last week where I got to share some of our new work from the lab! 🧠 Really enjoyed the discussions and meeting many amazing researchers, including some old friends 😊 Thanks to @David Loane and the TCD Biochemical society for the lovely invitation

submitted 37 days ago • 0 comments

Thrilled to be at #ADPD2025 in Vienna ☀️ Thanks to everyone who came to our session on innate immunity yesterday! Really enjoyed the discussions after on our findings on #metabolism & #microglia function in #alzheimer’s disease I’ve learned a lot at this meeting - looking forward to Copenhagen 2026 🧠

submitted 57 days ago • 0 comments

Intermittent Fasting Increases Sex Drive in Male Mice: An Approach for Low Libido in Humans? Current findings could point the way for new therapy option / Serotonin plays key role. Hot off the press from our Bonn based group of Dan Ehninger. 👉 www.cell.com/cell-metabol...

submitted 64 days ago • 1 comment

This month the McManus lab turns 1! 🎉 It’s been an amazing year, from starting out with an empty lab space to having our first co-authorships, grant awards and successful student projects 📄 Delighted to work with such a wonderful team of scientists on #alzheimersdisease and #dementia research 🧠

submitted 65 days ago • 1 comment

Visit the #exhibition "What the Health - One World. Your Health!" at the Museum Koenig in #Bonn. Check out the #events surrounding the exhibition and discover how your health and the health of the planet are connected 🌍 Learn more about the program here: bonn.leibniz-lib.de/de/ausstellu...

submitted 66 days ago • 0 comments

🚨 Apply now! We invite you to apply for this year's International School of Advanced Immunology taking place September 14 - 19 at Maria Laach, Germany. Visit our website for more information: www.advanced-immunology.net #international #school #immunology

submitted 72 days ago • 0 comments

Happy St Patrick’s Day! And what a lovely surprise from the lab, who all wore green this morning ☺️☘️

submitted 76 days ago • 0 comments

I am overjoyed to present our latest paper on Autophagy in CD8 Tcells! www.nature.com/articles/s41... It was, as all ‘sciencing’ is, a huge team effort. I will try to do it some justice in the following thread 😊 1/n @cantrell-lab.bsky.social @immpres.bsky.social @ajmhowden.bsky.social

submitted 92 days ago • 2 comments

Check out the latest episode from @immunosens.bsky.social where I chat about our research on #microglia, #NLRP3 and immunometabolism in #Alzheimer’s disease that was published this month in @cp-immunity.bsky.social

submitted 95 days ago • 0 comments

Five days of indulging in chocolate bars, crisps and other junk foods can lead to lingering changes in brain activity, a study shows1. The resulting brain patterns are similar to those seen in people who have obesity. https://go.nature.com/3F61B4o

submitted 96 days ago • 7 comments

Happy to share our first review from the McManus lab! 🥳 Special thanks to my PhD student & 1st author @nehalonkar.bsky.social & our co-author & collaborator Eicke Latz 📄 We summarise the key role of #metabolism on microglial function in health & #neurodegeneration 🧠 pubmed.ncbi.nlm.nih.gov/39936491/

submitted 103 days ago • 1 comment

2nd Brazilian-German Immunology Workshop Vienna, Austria August 15-16, 2025 DEADLINE for application: March 1 Pls apply to Tim Sparwasser (sparwasser.office’at’uni-mainz.de) or Bernardo Franklin (franklin’at’uni-bonn.de) by March 1 2025, stating the title of the lecture and a half-page abstract.

submitted 105 days ago • 0 comments

Job Opportunity Prof. Dominic Lemken is seeking a PhD candidate to research Consumer Behavior and Food Choices as part of our SFB! If you are passionate about #ConsumerBehavior and #FoodEconomics find out more here: www.uni-bonn.de/de/universit...

submitted 108 days ago • 0 comments

Another fantastic shot from @roisinmcmanus.bsky.social at the mechanisms of activation and modulation of the #NLRP3 inflammasome! Congratulations to the McManus team at the @dzne.science and my dear friends at the iii @unibonn.bsky.social! Fantastic work! www.cell.com/immunity/ful...

submitted 109 days ago • 0 comments

Temple University @temple.edu in Philadelphia is recruiting for a Assistant or Associate Professor - Tenure Track Faculty to work on seeking Therapeutic targets for Alzheimer's Disease. Closing date: 9th March www.dementiaresearcher.nihr.ac.uk/job/assistan...

submitted 112 days ago • 0 comments

🎉 Huge congratulations to @roisinmcmanus.bsky.social and Michael Heneka on this exciting study uncovering a novel role for NLRP3 in regulating microglial metabolism and phagocytosis to promote Alzheimer’s disease progression www.cell.com/immunity/abs...

submitted 114 days ago • 0 comments

Join us along with The Rainwater Charitable Foundation and CurePSP for #Tau2025, Apr. 24-25 in London or online! Be a part of the conversation as leading experts work to address the future of tau research. Register now: alz.org/Tau

submitted 114 days ago • 0 comments

Congratulations to @roisinmcmanus.bsky.social from DZNE in Bonn on her newly published paper in Immunity: "NLRP3-mediated glutaminolysis controls microglial phagocytosis to promote Alzheimer’s disease progression" 👉 doi.org/10.1016/j.im... 👉 www.dzne.de/en/news/pres...

submitted 117 days ago • 0 comments

The UK Dementia Research Institute @UKDRI is seeking an outstanding established academic to take the position of Centre Director, at the level of Clinical or non-Clinical Professor at Cardiff University. Closing date: 20th March www.dementiaresearcher.nihr.ac.uk/job/centre-d...

submitted 117 days ago • 0 comments

Whether you feel a sudden urge to discuss your recent research findings OR have completely missed the abstract submission OR have just discovered this fabulous congress: Submit your Late Poster and/or register here: www.nwg-goettingen.de/2025/default... between 👉 03 – 20 February 2025 👈

submitted 118 days ago • 0 comments

NLRP3-mediated glutaminolysis controls microglial phagocytosis to promote Alzheimer’s disease progression: Immunity www.cell.com/immunity/ful...

submitted 117 days ago • 0 comments

NLRP3-mediated glutaminolysis controls microglial phagocytosis to promote Alzheimer’s disease progression www.cell.com/immunity/ful... @cp-immunity.bsky.social @roisinmcmanus.bsky.social

submitted 117 days ago • 0 comments

I am thrilled to share our latest article that has been published in @cp-immunity.bsky.social. We describe a new role for NLRP3 outside of its #inflammasome complex, where it can regulate microglial #metabolism & key metabolites that affect the epigenetic landscape(1) www.cell.com/immunity/ful...

submitted 117 days ago • 8 comments