ygilad.bsky.social - Profile | ThreadSky | a Reddit-style client for Bluesky

Absolutely thrilled to see Dr. Brandon Gaut receive the inaugural @genetics-gsa.bsky.social Mentorship Award! 🏆🎉 Brandon brings humanity back to science, supports inclusive training, and pushes back on the publish-or-perish culture. So well deserved—congrats! 👏🙌 genestogenomes.org/distinguishe...

submitted 2 days ago • 0 comments

It was fun to write this piece with such a great team of colleagues in the field! Also grateful for discussions and feedback from @anshulkundaje.bsky.social @avsecz.bsky.social

submitted 7 days ago • 0 comments

My book, An Intuitive Primer on Effective Functional Genomics Study Design, is published! I’d really appreciate it if you could help spread the word, and I’d love to hear your thoughts and feedback. I hope people will find it useful. It’s available on Amazon: tinyurl.com/mx2hewen

submitted 123 days ago • 7 comments

🎉 This paper has been a long time and a labour of love (and hardship) for multiple group members, but, finally: we MPRA'ed 25k introgressed variants (Denisovan and Neanderthal) segregating at allele frequencies > 0.15 in humans today to evaluate their potential to regulate gene expression.

submitted 15 days ago • 5 comments

Nice! Environmentally responsive eQTLs are enriched for being more distal and for constrained genes relative to conventional QTLs.

submitted 15 days ago • 0 comments

www.biorxiv.org/content/10.1...

submitted 15 days ago • 0 comments

Congratulations to my colleague, collaborator, and friend @jkpritch.bsky.social for his so well deserved election to the national academy of science! Only thing is... NAS: what took you so long..?!

submitted 20 days ago • 3 comments

It's his favorite movie. He recognizes the music and he'll come to watch. Flow

submitted 46 days ago • 0 comments

New interview in the University TImes at Pitt based on my interview. utimes.pitt.edu/news/jeremy-...

submitted 70 days ago • 0 comments

Posted this last week but then the biorxiv site promptly went down for maintenance! Check out our new work using spatial txn to study heart transplant rejection! doi.org/10.1101/2025...

submitted 71 days ago • 0 comments

I am a bit surprised to see many posts on the response to the selection during Black Death paper without also a link to the response to the response, as it has been out for a long while now: www.nature.com/articles/s41... www.biorxiv.org/content/10.1...

submitted 71 days ago • 0 comments

I tested many free 'AI detection' tools, and they all highlighted large parts of my older RO1s (2010-2015) as written by AIs...

submitted 73 days ago • 2 comments

Fortunately, they didn't yet discover the trans-gender regulatory elements.

submitted 76 days ago • 1 comment

🧪 First posting of NIH grant review panels to #FederalRegister since Jan 21. Very limited. Just NIH Directors Awards (New Innovator, DP2) and one NIDDK study section, meeting dates range from March 24-April 4 www.federalregister.gov/public-inspe...

submitted 78 days ago • 0 comments

submitted 77 days ago • 0 comments

This was fun.

submitted 81 days ago • 1 comment

How do you study gene-environment (GxE) interactions in humans? Well, there's probably no way to avoid studying each exposure individually, but what about the cellular context? If you choose directed differentiation, you have to study GxE one cell type at a time. If you choose an organoid system -

submitted 82 days ago • 1 comment

Incredible to see this project taking shape! Good luck Mara&co! In parallel we are continuing to build genomes and polymorphism data for all Drosophila species! The combined resources will be a dream for understanding forces driving evolution on micro &macroscales journals.plos.org/plosbiology/...

submitted 85 days ago • 0 comments

www.nytimes.com/2025/02/21/s...

submitted 87 days ago • 0 comments

These are challenging times for science, but I'm happy to share a bright moment: our work is on the cover of Cell today. We built a compendium of human gut microbiomes integrating 168K worldwide samples, revealing patterns of microbiome variation across the globe www.cell.com/cell/current...

submitted 89 days ago • 4 comments

41/47 (87%) of NIH study sections are cancelled this week Frustrating to see all this good research stalled (& not funded) You can search for study sections that ‘did not meet as scheduled’ here with ones with * ⤵️ www.csr.nih.gov/RevPanelsAnd...

submitted 89 days ago • 10 comments

The court ordered that NIH grant funding be unfrozen, so The Regime found a way around it. For NIH grants to be funded, a review panel must rank them. In order for a review panel to meet, they must post it on the Federal Register. Submissions to the Federal Register are now on hold “indefinitely”.

submitted 89 days ago • 31 comments

Collaborators fired at USDA. Program officers fired at NSF. Study sections suspended indefinitely at NIH (also firings). It's impossible to just keep your head down and do the work, as the work and the people are vanishing in front of us. 🧪

submitted 90 days ago • 11 comments

gulfof.mapquest.com?name=Single+...

submitted 89 days ago • 1 comment

It looks like 8/8 study sections that were scheduled to begin today have been cancelled: www.csr.nih.gov/RevPanelsAnd...

submitted 90 days ago • 1 comment

I can afford to recruit a postdoc or staff scientist.

submitted 93 days ago • 0 comments

Iterative improvement of deep learning models using synthetic regulatory genomics www.biorxiv.org/content/10.1...

submitted 96 days ago • 0 comments

One often overlooked aspect of university endowments is how much is leveraged against debt. I don’t know the details everywhere, but in the institutions I’m familiar with, that fraction is quite considerable, making endowment spending far less flexible than it might seem at first glance.

submitted 99 days ago • 0 comments

Press release by the appropriations subcommittee on NIH budget slashing by @delauro.house.gov 🙏

submitted 99 days ago • 0 comments

We need a PR firm. We can't even get the message that 0.6/1.6 is not 60% across.

submitted 100 days ago • 1 comment

Imagine a family with 2 earners. One salary comes with strict rules: can only be used for groceries and utilities, not rent, daycare, or internet. The other salary covers everything else that keeps the household running. Now imagine that second salary disappears. That’s NIH IDC. And now it’s gone.

submitted 101 days ago • 0 comments

I really loved being a scientist.

submitted 101 days ago • 0 comments

Private biomedical research philanthropic organization HHMI knuckles under without a shot fired drugmonkey.scientopia.org/2025/02/07/p...

submitted 101 days ago • 2 comments

Excited to post my first #skySplain about our recent work published yesterday in Nature Genetics! www.nature.com/articles/s41.... One of the first authors of this study - Annika Vannan – actually wrote this breakdown, but she's not yet over here on bluesky and asked me to post!

submitted 105 days ago • 3 comments

It’s publication day for ENDS OF THE EARTH! Important times to communicate the scientific impact, beauty, and fragility of Earth’s polar regions. Vital, too, to communicate the impact and necessity of basic science research. 🧪 💙📚 Here’s an audio sampler: youtu.be/Tf3iOYx15UI?...

submitted 105 days ago • 5 comments