ygilad.bsky.social
Associate Dean for data science, and Professor of Medicine and Human Genetics at the University of Chicago.
108 posts
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782 following
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haven't had anyone in Chicago from your lab in a while...!
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This is such an exciting project! Huge thanks to Wenhe Lin, @jmpopp.bsky.social, @radster95.bsky.social, Olivia Allen, Jonathan Burnett, and to @alexisbattle.bsky.social, @ygilad.bsky.social, and Matthew Stephens for their mentorships! Check out our preprint for more!
www.biorxiv.org/content/10.1...
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For what it's worth, the printed version is available from multiple stores.
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Sorry, just Kindle (which was open when I made that decision...)
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that's was my conclusion! :)
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There's nothing to see. I used to live here you know....
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studies of regulatory variation and GxE interactions in the heart. here's the preprint: www.biorxiv.org/content/10.1...
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cell culture that can be established in less than 2 weeks, and includes practically all the cardiac cell types that can be found in the heart, or in a 3 months' old cardiac organoid. The cardiac HDCs are not a good model for studies of heart physiology and function, but may be a great mode for -
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work with organoids. We propose a new model - heterogeneous differentiating cultures (HDCs). These are guided (rather than directed) cultures that establish a complex and heterogeneous collections of cell types. We recently reported the properties of a cardiac HDC version:
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following by single cell sequencing, you can characterize GxE in many cell types, but organoids take a long time to establish, are expensive, and are difficult to dissociate. The GxE framework requires collecting data from a population sample, which makes it quite challenging to -
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watching without your commentary would not be the same...
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:-)
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comfirmed?
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Thanks!