How a fat in our diet (omega-6 linoleic acid)—a dietary long-chain polyunsaturated fatty acid) has the potential to promote tumor growth www.science.org/doi/10.1126/... www.science.org/doi/10.1126/... @science.org - ThreadSky

erictopol.bsky.social • 15 days ago

How a fat in our diet (omega-6 linoleic acid)—a dietary long-chain polyunsaturated fatty acid) has the potential to promote tumor growth https://www.science.org/doi/10.1126/science.adw1956
https://www.science.org/doi/10.1126/science.adm9805
@science.org

Comments

mickiemo.bsky.social•15 days ago

Ugh I eat plant based, so nuts everyday are part of my diet.

lynalraune.bsky.social•15 days ago

Interesting! But because everyone loves hating on linoleic acid: given its cardiovascular benefits, dietary limits require careful evaluation, especially because we have studies finding no or even protective effects on breast cancer! Actual outcomes!

saraparedesrn.bsky.social•15 days ago

The article talked about this affecting triple-negative cancer tumors (rather than estrogen positive) and suggests it may explain "heterogeneous responses of distinct breast cancer subtypes to dietary fats." and recommends more research distinguishing breast CA types. No dietary limits recommended.

lynalraune.bsky.social•15 days ago

Yes! My response was aimed at the "Omega-6s are inflammatory, cause cancer, and seed oils will kill you" crowd, who love to run with articles like this. I didn't want to suggest the article makes dietary recommendations.

texwiller.bsky.social•15 days ago

Linoleic acid is an essential fatty acid. That is, our body do not produce it nor is able to produce it.
Therefore it has to be assumed with diet.
As for many other carcinogen, the actual risk is a matter of dose

saraparedesrn.bsky.social•15 days ago

I appreciate access to the abstract. Even though I love data, I don't always go to the full article.

knudsonk.bsky.social•14 days ago

Guess we should stop recommending evening primrose oil (gamma linolenic acid) as a benign supplement for breast pain….

yurivs.bsky.social•15 days ago

Given that mTORC1 is a key regulator of cell growth, the link between diet and cancer opens new opportunities for nutritional interventions in therapy. could limiting ω-6 intake be an effective strategy for slowing tumor growth in humans

mstoodley.bsky.social•15 days ago

Too bad about the paywall.

sequencemyneuro.bsky.social•14 days ago

This is interesting, but mTor promotes all kinds of growth, including neuroplasticity and immune cell proliferation. You’d expect this to be a general effect, so omega 6 may also have beneficial effects on these other pathways via mTor eh?

Comments

Posting Rules

Reply