blacoste.bsky.social - Profile | ThreadSky | a Reddit-style client for Bluesky

blacoste.bsky.social

Senior Scientist, Associate Professor & Program Director @ OHRI & University of Ottawa 🇨🇦. Fascinated by vascular & metabolic causes of neurodevelopmental disorders, SciArt and the night sky 🔬 🎨 🔭 Follow for 🧪 news and more! Look for #cerebrovascular

373 posts 1,232 followers 299 following

Posts 31 Comments 19

New work by Joy Zuchero’s team at Denali Therapeutics #BloodBrainBarrier #Therapeutics

submitted 21 hours ago • 0 comments

Correction suggested by Canadians, using ancient language #Resist

submitted 3 days ago • 0 comments

The Eastern Veil Nebula (NGC 6992) is a supernova remnant, giant cloud of heated and ionized gas and dust situated ~2,400 light-years away from us. #Astrophotography #Nature

submitted 6 days ago • 1 comment

submitted 6 days ago • 0 comments

Don't get me wrong, but this paper's title is a mouthful 😅 #BloodBrainBarrier #Microglia #cerebrovascular

submitted 6 days ago • 0 comments

Great new work by Brian MacVicar's team, showing that pericytes and perivascular fibroblasts are distinct subpopulations of stromal progenitor cells in the adult brain that coordinate revascularization and scar formation after injury. #cerebrovascular #stroke #pericytes

submitted 8 days ago • 0 comments

New study shows that microglial CD39-initiated breakdown of extracellular ATP plays in an important role in the regulation of cerebrovascular reactivity. #cerebrovascular #microglia #ATP

submitted 9 days ago • 1 comment

🥁 The wait is over, a winner is announced ! In the battle for the best blood-brain barrier, the toad is victorious over the axolotl ! #BloodBrainBarrier #Amphibians

submitted 10 days ago • 2 comments

#BloodBrainBarrier #Neuroinflammation

submitted 10 days ago • 0 comments

submitted 11 days ago • 1 comment

New study in which authors establish, validate, and apply a choroid plexus spheroid model to study blood-CSF barrier function in lupus.

submitted 12 days ago • 0 comments

#BloodBrainBarrier

submitted 14 days ago • 0 comments

Endothelial Pannexin1 overexpression impairs ischemic stroke outcome #stroke #cerebrovascular

submitted 15 days ago • 0 comments

New review exploring bidirectional communication between the brain and the retina #Brain #Endothelium

submitted 15 days ago • 0 comments

The Crab Nebula is a supernova remnant located 6500 light-years away from us. Charles Messier mistook this nebula for Halley's Comet, which inspired him to create his famous catalog of deep sky objects. The Crab Nebula became "Messier 1" (or M1). #Astrophotography #Nebula #Nature

submitted 16 days ago • 0 comments

Pla1a and Cox4i2 genes could be new markers for brain pericytes, according to this new study #Pericytes #Markers #CellBiology

submitted 16 days ago • 0 comments

What's better than talking about metabolism, the blood-brain barrier and neurological disorders all at once? Check this new review 👇 #BloodBrainBarrier #cerebrovascular

submitted 17 days ago • 0 comments

Please consider attending the 2025 ECNP Congress in Amsterdam, we have a nice session on October 14th (S8. Vascular function and cognitive health across the lifespan) chaired by @maburto.bsky.social ! www.ecnp.eu/congress2025...

submitted 18 days ago • 0 comments

New study published in @naturecomms.bsky.social shows a link between #Autism (in this case Shank3 mutation) and #BloodBrainBarrier integrity, following our foot steps linking endothelial abnormalities and autism. Very exciting ! (we are actually working a something similar)

submitted 18 days ago • 2 comments

Super cool new review by @caromenard666.bsky.social’s team on neuro-glio-vascular alterations #cerebrovascular

submitted 20 days ago • 1 comment

Role of #BloodBrainBarrier dysfunction in the development of poststroke epilepsy

submitted 21 days ago • 0 comments

www.nature.com/articles/s41... #BloodBrainBarrier #Zebrafish

submitted 22 days ago • 0 comments

Scientist going grant writing mode

submitted 23 days ago • 0 comments

www.biorxiv.org/content/10.1...

submitted 23 days ago • 0 comments

New study led by @cathnaledi.bsky.social showing that physical exercise improves #cerebrovascular function in mice with genetic risk for Alzheimer’s disease.

submitted 24 days ago • 0 comments

www.nature.com/articles/s41...

submitted 24 days ago • 0 comments

Very interesting study led by Nicola Allen at the Salk Institute, elegantly showing that astrocytes contribute to molecular and functional changes associated with Fragile X Syndrome #astrocyte #glia www.biorxiv.org/content/10.1...

submitted 24 days ago • 0 comments

Fantastic new work led by @milenevandal.bsky.social showing that loss of brain endothelial CD2AP in mice alters memory and cerebrovascular function. Interestingly, mutations in CD2AP are known to predispose to Alzheimer’s disease! #cerebrovascular

submitted 24 days ago • 1 comment

Here is my galaxy image best-of. Truly incredible what anyone can capture (with the right gear...) from a light-polluted suburban backyard 🤩 #Astrophotography

New work by Joy Zuchero’s team at Denali Therapeutics #BloodBrainBarrier #Therapeutics

Correction suggested by Canadians, using ancient language #Resist

The Eastern Veil Nebula (NGC 6992) is a supernova remnant, giant cloud of heated and ionized gas and dust situated ~2,400 light-years away from us. #Astrophotography #Nature

Don't get me wrong, but this paper's title is a mouthful 😅 #BloodBrainBarrier #Microglia #cerebrovascular

Great new work by Brian MacVicar's team, showing that pericytes and perivascular fibroblasts are distinct subpopulations of stromal progenitor cells in the adult brain that coordinate revascularization and scar formation after injury. #cerebrovascular #stroke #pericytes

New study shows that microglial CD39-initiated breakdown of extracellular ATP plays in an important role in the regulation of cerebrovascular reactivity. #cerebrovascular #microglia #ATP

🥁 The wait is over, a winner is announced ! In the battle for the best blood-brain barrier, the toad is victorious over the axolotl ! #BloodBrainBarrier #Amphibians

#BloodBrainBarrier #Neuroinflammation

New study in which authors establish, validate, and apply a choroid plexus spheroid model to study blood-CSF barrier function in lupus.

#BloodBrainBarrier

Endothelial Pannexin1 overexpression impairs ischemic stroke outcome #stroke #cerebrovascular

New review exploring bidirectional communication between the brain and the retina #Brain #Endothelium

The Crab Nebula is a supernova remnant located 6500 light-years away from us. Charles Messier mistook this nebula for Halley's Comet, which inspired him to create his famous catalog of deep sky objects. The Crab Nebula became "Messier 1" (or M1). #Astrophotography #Nebula #Nature

Pla1a and Cox4i2 genes could be new markers for brain pericytes, according to this new study #Pericytes #Markers #CellBiology

What's better than talking about metabolism, the blood-brain barrier and neurological disorders all at once? Check this new review 👇 #BloodBrainBarrier #cerebrovascular

Please consider attending the 2025 ECNP Congress in Amsterdam, we have a nice session on October 14th (S8. Vascular function and cognitive health across the lifespan) chaired by @maburto.bsky.social ! www.ecnp.eu/congress2025...

New study published in @naturecomms.bsky.social shows a link between #Autism (in this case Shank3 mutation) and #BloodBrainBarrier integrity, following our foot steps linking endothelial abnormalities and autism. Very exciting ! (we are actually working a something similar)

Super cool new review by @caromenard666.bsky.social’s team on neuro-glio-vascular alterations #cerebrovascular

Role of #BloodBrainBarrier dysfunction in the development of poststroke epilepsy

www.nature.com/articles/s41... #BloodBrainBarrier #Zebrafish

Scientist going grant writing mode

www.biorxiv.org/content/10.1...

New study led by @cathnaledi.bsky.social showing that physical exercise improves #cerebrovascular function in mice with genetic risk for Alzheimer’s disease.

www.nature.com/articles/s41...

Very interesting study led by Nicola Allen at the Salk Institute, elegantly showing that astrocytes contribute to molecular and functional changes associated with Fragile X Syndrome #astrocyte #glia www.biorxiv.org/content/10.1...

Fantastic new work led by @milenevandal.bsky.social showing that loss of brain endothelial CD2AP in mice alters memory and cerebrovascular function. Interestingly, mutations in CD2AP are known to predispose to Alzheimer’s disease! #cerebrovascular

Here is my galaxy image best-of. Truly incredible what anyone can capture (with the right gear...) from a light-polluted suburban backyard 🤩 #Astrophotography

www.pnas.org/doi/10.1073/... #BloodBrainBarrier #Metabolism

For pericyte lovers www.researchsquare.com/article/rs-5...