charleslawrence.bsky.social - Profile | ThreadSky | a Reddit-style client for Bluesky

🆕 NHS England and local government have announced the world’s first #Gonorrhoea vaccine programme for eligible patients, with support from UKHSA. The vaccine, already used for meningococcal B, could protect against gonorrhoea by up to 40% and help fight #AntibioticResistance.

submitted 3 days ago • 2 comments

According to reports by @maxkozlov.bsky.social at @nature.com, #RachelRiley, a former #McKinsey consultant, #WoffordCollege grad, #RhodesScholar at @ox.ac.uk is the #DOGE flunkie who is responsible for killing many NIH grants. Not sure how she sleeps at night. www.nature.com/articles/d41...

submitted 2 days ago • 0 comments

Interesting preclinical data from Moderna for the VRBPAC meeting considering strain updates. There does seem to be a meaningful difference in protection between KP.2 vs. LP.8.1 for naive, but not experienced mice. www.fda.gov/media/186595...

submitted 2 days ago • 2 comments

Proximal Origin wasn’t a coverup. It was Kristian et al’s scientific opinion based on limited data (but held up well). Scientists have a right to freely express their opinions, on Slack & in papers. This isn’t “bad behavior.” It was scientists collaboratively examining the evidence. IOW, their jobs

submitted 3 days ago • 4 comments

The US doesn’t have universal health insurance for all citizens like every other country. Let’s do that before cutting access to life-saving vaccines. If you don’t have insurance you might have undiagnosed diabetes or hypertension, and so won’t be eligible when you should be eligible for vaccine

submitted 4 days ago • 3 comments

I need every single journalist covering vaccine stuff at the FDA to be explicit about this. Thank you @katherinejwu.com. www.theatlantic.com/health/archi... There is a genuine open question regarding the degree of benefit for otherwise healthy kids to get seasonal COVID-19 boosters.

submitted 3 days ago • 10 comments

Do not underestimate RFK Jr.'s determination to eliminate all vaccines, as he was lying through his teeth when he said he didn't want to take away anyone's vaccines. He will find ways to eliminate them. First, he will try to delicense specific vaccines, likely starting with HPV or hep B.

submitted 8 days ago • 41 comments

Makary and Prasad have a sounding board piece written in NEJM about the future of COVID-19 vaccine regulation at the FDA. Some thoughts:

submitted 4 days ago • 18 comments

Immunogenicity and Safety of Influenza and COVID-19 Multicomponent Vaccine in Adults ≥50 Years A Randomized Clinical Trial Combi vaccine outperformed each individual vaccine against Flu and COVID-19 jamanetwork.com/jour... 1/4

submitted 6 days ago • 1 comment

This is such an important shift. For many years the catholic church withheld support for HPV vaccination which prevents cervical cancer. 119,000 women die from this cancer in Africa every year. This full throated support of the HPV vaxx by the church will help uptake. nation.africa/kenya/health...

submitted 8 days ago • 18 comments

I had covid in my third trimester with my first born and ended up with critical oligohydramnios and an urgent c section with decreased fetal movement Amniotic fluid was totally normal literally the week before I had covid. It was only caught bc my doc didn’t like that I had lost weight

submitted 9 days ago • 1 comment

#RSV rates in infants are falling. Hospitalizations are down 28 % and 43 % for infants less than 7 months in two different networks, as reported in this week's MMWR. This is real world evidence that maternal immunization and MAbs are protecting this vulnerable populations - #MedSky.

submitted 16 days ago • 3 comments

Seems very reckless to ignore Vinay Prasad is someone with profound, open antipathy to regulators and esp CBER simply because he was "charming" in his recent speech. Guess what- people who have advanced their career to the levels of Makary and Prasad know how to be charming when they need to be

submitted 15 days ago • 8 comments

These people really want kids sick. Hepatitis B is not just a “sexually transmitted and IV drug user disease” like Means claims here. If she had ever completed medical training she might know that up to 40% of HepB infections are actually acquired in childhood & kill thousands of Americans per year.

submitted 16 days ago • 73 comments

If hepatitis B is contracted in infancy there is a 90-95% chance of it progressing in to the chronic form which results in liver cirrhosis and cancer. As few as 16 DNA copies/mL of blood have been shown to be sufficient for transmission.

submitted 15 days ago • 3 comments

Last year, Ben Mazer wrote this piece about the revenge of the Covid contrarians all now ensconced as leaders of public health, science & healthcare. but they’re a whole lot of fellow travelers among the liberal establishment who should take some of the blame. 1/ www.theatlantic.com/health/archi...

submitted 15 days ago • 5 comments

www.nytimes.com/2025/05/06/h...

submitted 17 days ago • 0 comments

New EO banning “dangerous gain-of-function” experiments dropped Monday. Allow me to break out my deranged anti-vax kakistocrat translator. Will this improve the safety & security of biological research? Hell yes, because biological research won’t exist anymore!

submitted 17 days ago • 8 comments

Absolute disaster of an interview from the new NIH Director - really most of you folks out here could do a better job. He comes across as having a huge chip on his shoulder, holding grudges, a bit of a persecution complex, & lack of grasp of NIH/political realities. www.science.org/content/arti...

submitted 18 days ago • 2 comments

Doubt-Peddling YouTube Doctor Named FDA’s New Vaccine Chief www.importantcontext.news/p/vinay-pras...

submitted 17 days ago • 1 comment

Vinay Prasad spent his career fighting against these sort of shortcuts. I guess “gold standard science” is only going to apply to vaccines.

submitted 17 days ago • 4 comments

I talked to @kakape.bsky.social about this for @science.org, along with many other colleagues including those with different views on regulatory oversight. We all agree: it’s too vague to be implemented, effective, or enforceable. www.science.org/content/arti...

submitted 17 days ago • 7 comments

Trump‘s EO on gain-of-function work underscores how differently this administration treats the risk of a dangerous virus in a lab vs. say on a dairy farm. “In this administration’s outlook, diseases come from labs, not nature, so they aren’t doing anything about it“, says @ggronvall.bsky.social 🧪

submitted 17 days ago • 6 comments

RFK announced a $500m flu vaccine development program...that seems designed to fail. -50yr old technology that's riskier to use than newer methods -eschews candidate vaccines backed by more evidence -the platform was modified decades ago, partly bc of side effects kffhealthnews.org/news/article...

submitted 17 days ago • 5 comments

Journalists writing on Vinay Prasad, I strongly encourage you to show videos of him in his own words to your readers. I have a decent collection and can help you curate. Let your readers see who he really is. youtu.be/_HZDNG9gO1Q

submitted 18 days ago • 3 comments

A new era at NIH. www.theatlantic.com/health/archi...

submitted 17 days ago • 1 comment

I only see two possible explanations. Either Bhattacharya lied, or he genuinely didn’t know because RFK Jr. and Trump don’t include him in discussions of major decisions about NIH. In other words, he’s a liar or a powerless figurehead. Take your pick.

submitted 18 days ago • 5 comments

I’m not really sure what to do about the fact that it has become so normalized to just reject any facts people don’t like and reconstruct events to fit our preconceived ideas instead of modifying them. Happy to be corrected if I am mistaken but I feel like it wasn’t always like this.

submitted 22 days ago • 5 comments

Couldn’t disagree more. Medicine and the real world are inextricably intertwined. To advocate for our patients is to engage beyond simple academia. Essentially, this article argues we should remain detached in our ivory towers. THAT is what causes decreased trust.

submitted 19 days ago • 23 comments

The Vaccine Integrity Project has published a Viewpoint on the proposed changes to vaccine clinical trials and vaccine safety monitoring:

submitted 19 days ago • 0 comments

There aren’t words to adequately describe the extent to which this is a step down from Peter Marks. Prasad has previously compared the US pandemic response to the behavior of Nazis and is a leader in methodolatry who feigns ignorance about when RCTs are appropriate. cancerletter.com/the-cancer-l...

submitted 18 days ago • 3 comments

He literally doesn’t understand how an EUA works. He tried to argue that EUA should not be “extended” to include children for pediatric COVID vaccines because COVID wasn’t an emergency. EUAs are given when there is a declaration of an emergency by HHS secretary. Broadening the age indication ≠…

submitted 18 days ago • 2 comments

tl;dr- egotistical edgelord intoxicatingly enamored with the (false) idea that he's far smarter than everyone else and therefore superior

submitted 18 days ago • 9 comments