ianywonglab.bsky.social - Profile | ThreadSky | a Reddit-style client for Bluesky

Quite an essay on the basis of cancer entitled "The End of the Genetic Paradigm of Cancer" @plosbiology.org arguing against the primacy of somatic mutations (traditional model) and cells, invoking gene regulatory networks and tissue journals.plos.org/plosbiology/...

submitted 2 days ago • 4 comments

Looking forward to stimulating talks on "Hacking the Nervous System" for the Regional Meeting of the US National Academy of Engineering @tejaladesai.bsky.social

submitted 6 days ago • 0 comments

I would like to share my recent interview with The Brown Daily Herald, where I talk about how I combine #science and humor through Biocomicals. www.browndailyherald.com/article/2025...

submitted 7 days ago • 0 comments

More Nikon NSPARC confocal testing at the @ncis-marseille.bsky.social: super-resolved live-cell imaging (1 frame every 10 seconds) of a COS-7 cell labeled for DNA (blue), endosomes (pink) and actin (gray) using probes from @spirochrome.com

submitted 15 days ago • 6 comments

Join us tomorrow, Feb. 26th at 3pm EST for a #TissueTalk with Brown University Dean and Prof. Tejal Desai @tejaladesai.bsky.social on "Tuning the 'Structure' of Biomaterials for Cell-Based Therapy." See you soon! RSVP/zoom link: bit.ly/tissuetalks

submitted 23 days ago • 1 comment

Warm-ish winter weather in Providence with a rubber duck flotilla in the lower right 🟡

submitted 22 days ago • 0 comments

Our Immunology and Cancer Biology Mini-Symposium gets underway at @BrownMedicine @BrownUnivHealth #LegorretaCancerCenter

submitted 23 days ago • 0 comments

Excited to start collaborating on Anti-Cancer Immunoengineering with @weldeiry.bsky.social www.brown.edu/academics/ib...

submitted 24 days ago • 1 comment

Honored to be interviewed by @naturemethods.bsky.social about my lab philosophy Many thanks to Vivien Marx @vivienm.bsky.social for writing this and the many lab members past and present who have collaborated scientifically. nature.com/articles/s41...

submitted 27 days ago • 1 comment

My latest Research Highlight is now online @natrevmcb.bsky.social! The Brangwynne lab uncovers how chromatin heterogeneity influences condensate formation during #CellMigration, revealing intriguing insights into nuclear mechanics. 🔗 go.nature.com/3ZpwGH7 OG Paper: go.nature.com/3Baxpnn

submitted 105 days ago • 0 comments

Lab Values “We believe that diversity of background, identity, and opinion are essential to maximize scientific innovation.” Nature Methods Article: doi.org/10.1038/s415... Sammy Katta's Lab Posters: www.sammykatta.com/diversity #AcademicSky #PhDSky

submitted 31 days ago • 1 comment

"Intrinsic electrical activity drives small-cell lung cancer progression" www.nature.com/articles/s41...

submitted 36 days ago • 0 comments

New paper from the lab🎈. Introducing Micro Immune Response On-chip (MIRO), a device that replicates tumors and their microenvironment to better understand responses to immunotherapies (cyan=immune cells, red=cancer, green=CAFs). www.nature.com/articles/s41... @ibecbarcelona.eu

submitted 41 days ago • 7 comments

"Imagine a DAPI-like stain, but for the extracellular matrix." That's basically how this work was pitched to me by Kayvon and Antonio a year or so ago. Now the final product really delivers. Read about their versatile label for ECM in living tissues here: www.nature.com/articles/s41...

submitted 42 days ago • 9 comments

Cells are full of protein machines. Most don’t act alone, but instead form part of larger multiprotein complexes. For example, epithelial tissues & organs assemble by virtue of the multiprotein machines mediating cell-cell adhesion or adhesion of cells to the underlying extracellular matrix 1/n 🧪

submitted 67 days ago • 20 comments

sunset on the main green

submitted 49 days ago • 0 comments

Self-generated gradients guide collective cell movement -but often different cell types must move together, e.g. in immune response. We develop a theory of self-generated chemotaxis in mixed populations -are there optimal principles for this cooperation?🤔 www.biorxiv.org/content/10.1...

submitted 70 days ago • 2 comments

#CellMigration for #FluorescenceFriday 🧪🔬 If a metastatic #cancer cell is offered 2 paths it decides very fast, bc it does matter where it goes... OTOH, if a non-cancer #cell is offered 2 options it takes some time to explore and decide. More in the paper: www.nature.com/articles/s41...

submitted 55 days ago • 2 comments

How a heart medication—digoxin—might help prevent cancer spread by dissolving clusters of circulating tumor cells www.nature.com/articles/s41...

submitted 55 days ago • 14 comments

Inspired by a brilliant Gordon conference on directed cell migration 🤔 Many thanks to Sally Horne-Badovinac and Robert Insall for all their hard work! @robinsall.bsky.social

submitted 59 days ago • 0 comments

Warming up for the upcoming #GRCCellMigration For me the best video to explain adhesion-dependent #CellMigration by Felix Donghwi Son More in the website felixvis.artstation.com #sciart #scicomm #ScienceSky #SciSky #cytoskeleton #FocalAdhesion

submitted 69 days ago • 3 comments

In our December By the Numbers, Sujit Datta discusses how scaling arguments, dimensional analysis, and chemical engineering fundamentals can be used to describe microbial swimming. #chemsky Article link ($): www.nature.com/articles/s44... Free read PDF: rdcu.be/d5MRz

submitted 70 days ago • 0 comments

The ear and the nose are squishy and stretchy thanks in part to ‘bubble wrap’ cells that provide extra cushioning and structural support to various body parts, a wide-ranging study shows. www.nature.com/articles/d41...

submitted 69 days ago • 0 comments

Researchers observe durotaxis, and its underlying mechanism, in amoeboid. https://buff.ly/4gFKPac

submitted 77 days ago • 0 comments

They don't make @nature.com papers the same anymore Exhibit A: 'PHOTOGRAPHS OF A TUMBLING CAT', 1894 (www.nature.com/articles/051...) Includes this line: 'The expression of offended dignity shown by the cat at the end of the first series indicates a want of interest in scientific investigation' 🙀

submitted 90 days ago • 7 comments

While our bodies seem static, our cells are constantly changing shape or on the move during tissue homeostasis or wound repair & even more dramatically during embryonic development, during events like gastrulation. Defining how cellular machines mediate these events is a key task for our field 1/n

submitted 110 days ago • 17 comments

Live imaging of zebrafish 🐟 embryogenesis acquired with our light-sheet #microscope #daxi 🔬 Microscope: doi.org/10.1038/s415... 🧪 Time-lapse data from our "Zebrahub" developmental atlas: www.cell.com/cell/fulltex... #FluorescenceFriday #zebrafish #AcademicSky #DevBio

submitted 97 days ago • 0 comments

Let's share some other classic, the beautiful Cells in culture film directed by Michael Abercrombie one of the father of quantitative cell imaging (University College London, 1955) is available here identity.wellcomecollection.org/works/z6h7jzv4

submitted 108 days ago • 2 comments

🎈New preprint! We study how single cells move up, down and about fibronectin gradients. Experiments by @icfortunato.bsky.social, theory by David Bruckner. Collaboration with @raimonsunyer.bsky.social and @ehannezo.bsky.social 👇https://biorxiv.org/cgi/content/short/2024.12.02.626413v1

submitted 107 days ago • 5 comments

Looking forward to Thursday's visit from Prof. Ritu Raman (MIT Mechanical Engineering) and her talk on engineered neuromuscular tissues (towards bio-robots!). @rituraman.bsky.social

submitted 108 days ago • 0 comments

One of my favorite images: a platinum replica electron microscopy shot of an unroofed cancer cell migrating along collagen fibers (blue). It beautifully captures the clathrin-coated pits (red, ~100 nm) and the intricate network of branched actin filaments (orange) 🔬

submitted 114 days ago • 4 comments

Back from a stimulating visit and seminar at Northwestern Biomedical Engineering and the Chan Zuckerberg Biohub Chicago (on the first snow of the winter)!

submitted 117 days ago • 0 comments

For #FluorescenceFriday, a found an old video of MDA-MB-231 cells in a dense collagen matrix dividing, acquired on a lattice lightsheet microscope at the @aicjanelia.bsky.social. Mitotic chromosomes are fun to watch! This was just a quick test video, hence the limited but still impressive quality.

submitted 117 days ago • 1 comment

Cells are strong & generate forces while interacting with their environment. Traction Force Microscopy has been instrumental in measuring these forces, revealing the underlying mechanics. Let's explore pioneering papers in this 🧵by @onenimesa.bsky.social & @juliaeckert.bsky.social

submitted 123 days ago • 1 comment

Slow-mo Calcium response! Here is a little neutrophil with a calcium sensor doing its best to respond to a chemoattractant! Work done by Evelyn Strickland inspired this! Check out her paper on self-extinguishing relay waves in neutrophil swarming www.sciencedirect.com/science/arti... #art #sciart

submitted 133 days ago • 0 comments

Happy 1st #FluorescenceFriday on #BlueSky! I'll reintroduce myself. My research interest is cell migration, be it cancer cell invasion or immune cell, and how the physical environment influences their behavior. I make lots of movies of moving cells so here is a macrophage at super-resolution.

submitted 124 days ago • 3 comments

Hi everyone! Kicking off my first #FluorescenceFriday here with a 3D SIM image of actin, and of course had to go with my favorite blue LUT (JDM Duo Intense Cyan) for Bluesky.

submitted 125 days ago • 6 comments

Quake, Stephen R. "The cellular dogma" Cell, Volume 187, Issue 23, 6421 - 6423 www.cell.com/cell/fulltex...

submitted 126 days ago • 0 comments

I started a list of people working broadly on cell adhesion and cell migration. I likely missed many, please drop me a message if you want to be added go.bsky.app/5Gzo7oZ

submitted 129 days ago • 27 comments