isabelmeister.bsky.social - Profile | ThreadSky | a Reddit-style client for Bluesky

Two big reveals in the world of #extracellularvesicles this week: Blebbisomes www.nature.com/articles/s41... and the ‘torn bag mechanism’ of small EV release from amphiectosomes elifesciences.org/articles/958...

submitted 21 hours ago • 0 comments

I’m happy to share that my PhD work is now out on #biorxiv. We propose an ‘on-demand release’ model for the release of the endocannabinoid 2-arachidonoylglycerol in extravellular vesicles (EVs) #lipidtime #neuroskyence #biosky 🔗 www.biorxiv.org/content/10.1... 1/5

submitted 150 days ago • 1 comment

Trump and his administration are now deciding how deep a rift to make in America’s scientific firmament. How long it takes to repair the damage, or whether that will be possible at all, depends on the extent of the damage they inflict now.

submitted 7 days ago • 1 comment

Lipid Signature of Motile Human Sperm: Characterization of Sphingomyelin, Ceramide and Phospholipids with a Focus on Very Long Polyunsaturated Fatty Acid https://www.biorxiv.org/content/10.1101/2025.02.17.638566v1

submitted 1 day ago • 0 comments

A truly depressing article in #Nature listing of all the damage done to #science in the US by the Trump administration in just one month 💔 for so many friends and colleagues there #solidarityforscience 🧪 www.nature.com/articles/d41...

submitted 2 days ago • 4 comments

Very proud to be part of that team - this was a really long term project with lots of amazing people!

submitted 2 days ago • 0 comments

Please spread the word! #metabolomics #lipidomics #nontargeted

submitted 2 days ago • 0 comments

Incredible opening plenary at the Queensland Mass Spectrometry Symposium 2025 #qmss2025 by @hecklab.bsky.social on mass spectrometry of individual ions 🤯 pubmed.ncbi.nlm.nih.gov/37279016/

submitted 3 days ago • 0 comments

What is the link between PFAS type contaminant and oxylipins? None? Well mass spectrometry low resolution identification can always messed up somehow, and revealed to the lipid community the long forgotten space left by the Trioxilins… A thread doi.org/10.1021/acs.... #epilipid #massspec #oxylipins

submitted 4 days ago • 2 comments

Reminder: the applications for the Q2 Empowerment Awards close February 23rd! Get your application in now 👇

submitted 4 days ago • 0 comments

I hear this has generated some fury on X, so would be pleased if people could keep sharing as it is an attempt to be clear about the free speech implications of my open letter.

submitted 3 days ago • 2 comments

Hi folks, I would like to know which EU universities are willing or planning to organise #standupforscience activities in solidarity with US scientists Please contact me if you are. Thanks for reposting!

submitted 3 days ago • 1 comment

I feel like I'm going insane every time I see a media story about DOGE that doesn't also mention the fact that the Government Accountability Office exists and performs the exact function that DOGE pretends to, only in a credibly constitutional, non-partisan, and conflict-of-interest-free manner

submitted 6 days ago • 186 comments

Thanks to all of the NIHers and their friends who reached out to me. I am still here (DM me or Signal jeremymberg.78) I still have a very incomplete picture but based on what I have been told, the damage to NIH and to many wonderful people who work(ed) there is/was impossible for me to imagine 1/n

submitted 6 days ago • 8 comments

There doesn't seem to be much we can do to support our fellow scientists in the US but we can at least lobby for this important signal to the world

submitted 8 days ago • 1 comment

If you know me, you know what I think of gen AI - it can automate some tasks and write decent code but can only ultimately rephrase the Internet. Yesterday I was (lazy/time-poor) so I tried Cerebras' Llama-3.1 interface. I think this is quite illustrative of gen AI chain-of-thought 🧵

submitted 8 days ago • 7 comments

Now almost 450 signatories to my open letter calling on the @royalsociety.org to stand up for its values & deal with the widespread concerns raised by Elon Musk's Fellowship. Please consider signing & sharing: forms.gle/miDciq35oxyw... List of signatories here: occamstypewriter.org/scurry/2025/...

submitted 10 days ago • 6 comments

1. Today the NIH director issued a new directive slashing overhead rates to 15%. I want to provide some context on what that means and why it matters. grants.nih.gov/grants/guide...

submitted 15 days ago • 271 comments

If you're looking for an insight into how things are going at NASA since Trump's regime started attacking it, here's astronomer & NASA employee Rose Ferreira on Threads. (Her now-removed interview is archived here at the Wayback Machine and it's well worth a read: web.archive.org/web/20231206... )

submitted 15 days ago • 13 comments

It's time to educate our neighbors about the importance of science funding. Local news papers still exist and are read by folks. Here is the op-ed I wrote for this week's "News of Orange", a local paper in Orange Co NC. Full text is on the alt-text 🧪

submitted 15 days ago • 9 comments

I am appalled by the ASM's decision to remove DEI content from their website. Here is my email to the American Society for Microbiology, @ASM.org asking them to put everything back as it was. If you are an ASM member, please consider writing them.

submitted 19 days ago • 13 comments

I want to expand on the extent to which IDEAA materials have been purged: I wrote an article last year for women’s history month on the history of women in antimicrobial development….DELETED.

submitted 20 days ago • 5 comments

Checked on the article I wrote about Juneteenth in 2023… ”under review”

submitted 20 days ago • 7 comments

I did a list of #WomeinSTEM working in #metabolomics & #lipidomics and #datascience please join or share with others, use it for conferences, media & networking, mentoring, supporting, anything that helps, 300+ women have joined docs.google.com/document/u/0...

submitted 22 days ago • 0 comments

Fast and Comprehensive Lipidomic Analysis using Supercritical Fluid Chromatography Coupled with Low and High Resolution Mass Spectrometry #JChromA www.sciencedirect.com/science/arti...

submitted 21 days ago • 0 comments

Academic Skyers: I am compiling a list of policies and statements from various universities about how they are handling the "pause" in terms of stopping expenditures (or not). Please respond to this post with your institution and materials. THANK YOU!

submitted 25 days ago • 148 comments

Aside from the Keynote, the presenters at the Showcase are exclusively non-faculty scientists. Presenters have gone on to secure postdoc/faculty positions, forge new collaborations, and publish their research. Abstract submissions are due on March 21st, 2025. www.cancermetabolismshowcase.org

submitted 26 days ago • 0 comments

A depressing read, but I think Gorski is on target here. Time to start counting up the folks who are trying to tell us that AKshully the NIH needs to be beaten into submission, etc.

submitted 26 days ago • 1 comment

Cancer cells ‘poison’ the immune system with tainted mitochondria www.nature.com/articles/d41...

submitted 30 days ago • 0 comments

Donate to Wikipedia. Do it today, and every time one of the broligarchs has a tantrum because he can’t buy it

submitted 32 days ago • 52 comments

fantastic new #lipidtime story from @ibudin.bsky.social and co: www.biorxiv.org/content/10.1... fiddling with sterol synthesis produces cool membrane properties, suggesting that evolution has selected not only for membrane ordering but also liq-liq phase separation!

submitted 45 days ago • 1 comment

I think the field needs to reconsider the widespread concept that microglia are The most important factor controlling synaptic pruning.🧠🧪 We offered our Perspective on whether they are hunters or gatherers of synaptic debris here www.nature.com/articles/s41...

submitted 45 days ago • 0 comments

Researchers spend approximately 45% of their time on administrative activities related to #grants rather than actual #research. The current #competition in research #funding has significant drawbacks; evidence-based improvements of the funding system are required: www.pnas.org/doi/10.1073/...

submitted 62 days ago • 19 comments

Why can a human tolerate a drug that globally inhibits transcription? Why do transcription inhibitors not cure cancer? Our first paper of 2025 may help explain (some) of this! So incredibly proud of @tobiaswilliams.bsky.social & Ewa Michalak who led the work! www.cell.com/molecular-ce...

submitted 51 days ago • 11 comments

"Isn't it the moment of most profound doubt that gives birth to new certainties? Perhaps hopelessness is the very soil that nourishes human hope; perhaps one could never find sense in life without first experiencing its absurdity." -Vaclav Havel

submitted 52 days ago • 31 comments

Psilocybin-Assisted Group Psychotherapy + Mindfulness Based Stress Reduction (MBSR) for Frontline Healthcare Provider COVID-19 Related Depression and Burnout: A Randomized Clinical Trial https://www.medrxiv.org/content/10.1101/2024.12.31.24319806v1

submitted 52 days ago • 0 comments

"In 2023 Elsevier began using AI during production without informing the board, resulting in many style and formatting errors, as well as reversing versions of papers that had already been accepted and formatted by the editors." very innovative, very cool

submitted 53 days ago • 24 comments

Really interesting long essay on Netflix & the streamers. www.nplusonemag.com/issue-49/ess...

submitted 55 days ago • 53 comments

☕This year, in our #CellDeath focus: Glover, Schreiner, Dewson & Tait reviewed the intersection of #mitochondria and cell death. #pyroptosis #ferroptosis #necroptosis #apoptosis 👉https://rdcu.be/d46gt www.nature.com/articles/s41...

submitted 56 days ago • 1 comment

Development and thorough evaluation of a multi-omics sample preparation workflow for comprehensive LC-MS/MS-based metabolomics, lipidomics and proteomics datasets #Talanta www.sciencedirect.com/science/arti...

submitted 60 days ago • 0 comments

Times are changing but order matters: Transferable prediction of small molecule liquid chromatography retention times Authors: Fleming Kretschmer, Eva-Maria Harrieder, Michael Witting, Sebastian Böcker DOI: 10.26434/chemrxiv-2024-wd5j8

submitted 61 days ago • 0 comments

Sex differences in neuron protection could reveal Alzheimer’s target. #Science "Study highlights the critical role of TLR7 in sex-biased Alzheimer’s-related demyelination" News news.cornell.edu/stories/2024... Paper www.science.org/doi/10.1126/...

submitted 59 days ago • 1 comment