Profile avatar
jj24.bsky.social
Retired physician, interested in science, food and travel. Husband, father and grandfather.
31 posts 72 followers 327 following
Prolific Poster
Conversation Starter

This week was the 1st publication using our immune cell sequencing to accurately make medical diagnoses. It has enormous implications, as I've reviewed here erictopol.substack.com/p/the-first-... @scottboydlab.bsky.social @science.org @anshulkundaje.bsky.social @maximzaslavsky.bsky.social

For decades, the US government has painstakingly kept American science #1 globally—and every facet of American life has improved because of it. The internet? Flu shot? Ozempic? All grew out of federally-funded research. Now all that's being dismantled. 1/ www.technologyreview.com/2025/02/21/1...

In a small trial, nearly half of pancreatic cancer patients who received an mRNA vaccine had no signs of relapse after three years. Dr. Vinod Balachandran from @mskcancercenter.bsky.social joins us to discuss the results and what they could mean for cancer treatment.

This...

This is a disaster for us all. No family will be spared the slowdown in biomedical innovation. apple.news/Ajq81nIg3Rp6...

In Connecticut - NIH FUNDING: $770M JOBS SUPPORTED: 6609 ECONOMIC ACTIVITY SUPPORTED: $1.68B

The NIH announced it will slash billions of dollars of support to universities and research centers. This is one of the biggest attacks on science we have ever seen. It could dismantle the biomedical research system, shut down clinical trials, and halt development of treatments.

www.nytimes.com/2025/02/06/h... This is criminal.

The promise of a personalized (neoantigen) vaccine for treating cancer, as seen by immune response bolstering against renal cell carcinoma in a Phase 1 trial nature.com/articles/d41... nature.com/articles/s41...

I wouldn't have anticipated this one! Preventing or treating hypertension through a gut microbiome intervention, in both mice and a pilot study in people www.cell.com/cell-metabol... @cellpress.bsky.social

As someone trained as a trade economist, it is my duty to share the 1929-1933 Kindleberger Spiral, showing the month-month decline in global trade due to the combined factors of the (global) Great Depression and retaliatory tariffs. Smooth Hawley is implemented mid-June 1930.

Organizations representing universities and medical schools have been distressingly quiet about potential funding freeze. Here is a statement from the American Association of University Professors www.aaup.org/news/stateme...

www.wired.com/story/life-s...

Learning the language of life with A.I. @science.org In today's essay, I review the phenomenal progress in foundation models of DNA, RNA, proteins, ligands, cells, their interactions, the Virtual Lab, and the aspiration for the Virtual Cell www.science.org/doi/10.1126/...

BREAKING NEWS: The FDA has approved Ozempic for patients with chronic kidney disease. This means the popular injection can be used to reduce the risk of kidney disease worsening, kidney failure and death from cardiovascular disease in patients with chronic kidney disease and diabetes.

Many of you may not be familiar with #NIH grants. Here are some facts to help you understand the magnitude of this disaster. 1) NIH grants are extremely difficult to get & not "free money". Researchers must have preliminary data & write detailed proposals. Mine was >200pages & took years to put

www.nytimes.com/2025/01/27/h... This is insane.

The sequence of SARSCoV2 was made available on Jan 10 2020. Exactly 11 months later on Dec 11th 2020 the first EUA was issued for an mRNA COVID vaccine. These vaccines saved over 20 million lives. None of this would have been possible without NIH funding & dedicated scientists. #ScienceMatters

@rachelbitecofer.bsky.social I agree with you. Most people only understand visuals that directly affect them. You see it daily in the ICU. See below. youtu.be/YbGOP0NJOQw?... This is the sound of no vaccine. Is this what you want for your kids?

Canadian MP Charlie Angus on Trump’s claim that Canadians would get better healthcare as the 51st state: This is my health card. I just walk into a hospital, give them my card, and I get free coverage. That’s how health care is delivered here. We don’t have people who pay and people who are denied.

bsky.app/profile/jj24... #medsky

youtu.be/YbGOP0NJOQw?... This is the sound of no vaccine. Is this what you want for your kids?

youtu.be/YbGOP0NJOQw?... This is the sound of no vaccine. Is this what you want for your kids?

More from inside NIH: Per a source with knowledge, for all internal research (of which there is like $10 billion worth or so), ALL purchasing shut down as of yesterday. That means gloves, reagents, anything involved with lab work, which means a lot of that work will stop.

#ICYMI: After years of heightened scrutiny by GOP lawmakers, NIH’s National Institute of Allergy and Infectious Diseases could be overhauled or effectively dismantled under the incoming Trump administration. By @annamaria.bsky.social

People are easier to break down if they think they are already ruined. We are not there. Grateful to Carl for this post reminding me of that. Don’t obey in advance & don’t surrender either. Do what you need to care for yourself & get ready to fight like hell for our profession & everyone’s health.

Started off this morning emailing my Senators and Congressman about the NIH and the potential damage being done by unnecessary disruptions. They need to hear from us loud and clear. Constituents matter to them as one of the primary purposes of a politician is to get re-elected (and its their job).

All NIH study sections canceled indefinitely. This will halt science and devastate research budgets in universities.

Trump has basically paused the work on the NIH for the time being. This is unprecedented and terrifying. The NIH drives the world’s health research and any pause delays cures. #MedSky www.science.org/content/arti...

Scientific advancements aside, this is economically irresponsible Every $1 spent by NIH generates $2.46 For example, in 2023, $47B in NIH spending generated ~$93B Halting NIH spending will LOSE the US a lot of money (and talent)

Hopeful news (as someone whose dad passed of Parkinson's): an existing cancer therapy is showing promise to stop the spread of Parkinson's disease. www.sciencealert.com/parkinsons-d...

Brain implant that could boost mood by using ultrasound to go under NHS trial