jonroberts.bsky.social
Research genetic counsellor. PhD in Science Communication.
Researching equitable genomic testing & genetics of neurdevelopmental disorders.
https://substack.com/@jonathanrob1985?utm_source=user-menu
1,680 posts
2,090 followers
727 following
Regular Contributor
Active Commenter
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This is a great thread. All that's in my head though with that image is
D'NA D'NA D'NA D'NA
D'NA D'NA D'NA D'NA
BATMAN!!!
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Funded by billionaires telling them the problem is not the ultra wealthy gobbling up all the assets but poor people with different coloured skin.
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They're just so bloody intelligent (octopuses) I'm amazed at how little attention this receives.
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It's being silly! More of it. I've noticed this with my kids. It has a wonderful ability to connect people.
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"The DNA of our language". Oof. I felt that right in my PhD.
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The LA situation is a big test of the regime's propaganda machine.
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Too long has Big Chair gone unchallenged
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He wants to highlight their beliefs
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Trump - "If there's any protester who wants to come out, they will be met with very big force."
Please tell us again- JD Vance - how it's the EU that has a freedom of speech problem.
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@millroad4people.bsky.social
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Counterpoint: no they're not
www.bylinesupplement.com/p/the-myth-o...
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We have radial abundance now. The tech billionaires just don't want to share.
They're like: we need all the power and money and resources right now but we promise there will be enough to go around soon. Trust us bro.
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I'm just getting through "more everything forever." It's a good read I think to help understand a lot of what is happening right now with silicon valley.
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Open AI headquarters right now
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There's been a radical shift to hard right popularism!
The BBC
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The great success of Farage and his political parties has always been to exert influence beyond their popular appeal.
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Thats reductio ad absurdum and you know it
There's a big difference between powers a government inherit and powers they would have to get though parliament.
I don't want the Government now to make power grabs only for those powers to end up in the hands of a minority Reform parliament
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It's like some smart arse QI answer
*Klaxon* Technically fascists don't wear uniforms
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Pointlessly unnecessary.
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And you. Good conversation. This topic can get bad tempered which doesn't help anyone!
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On patient education. This is obviously important. It's what I've spent much of my career researching. But I don't think patient education can substitute for suitable regulation and government oversight.
I respect your point of view. I just think we happen to disagree!
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Fair points. I think there is a big difference in using PRS for breast cancer for something like screening stratification, where you have other data to contextualise and make sense of the PRS, than embryo selection. In the later I think the predictive uncertainty is too high.
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If they don't work they should not be allowed. We wouldn't let a company offer embryo selection based on astrological readings.
In my view this needs government regulation. I don't think it's acceptable to regulate this via patient education.
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I accept this view has issues. What counts as "high certainty" and "clinically serious" is open to much interpretation. Others also think different and I accept people in good faith have very different opinions to me on this.
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The predictive value of genetics testing is far more circumspect than we realised. I realise this makes me quite conservative but in my view embryo testing should be reserved for high penetrance, high certainty (eg path variant with FH of condition) and clinically serious conditions.
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It's a fair point. I'd say
1. Trait selection matters. Anything like IQ should not be allowed
2. For things like cancer risk. Even for Mendelian conditions, the penetrance is proving far more variable as we do population studies.
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Plomin. Well. I think I might have a heart attack and die of not surprise.
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I wrote about the use of polygenic scores in education, where many of the same issues arise - of ethics and predictive value.
eastangliabylines.co.uk/news/educati...