juditarvelund.bsky.social - Profile | ThreadSky | a Reddit-style client for Bluesky

For decades, we underestimated the importance of our lymphatic vessels to suppress cancer and its spread. Here's a new, open-access, outstanding review rupress.org/jem/article/...

submitted 2 days ago • 8 comments

So happy to be off twitter and fully over here for months now.. How anyone can continue to post on a platform owned by someone who is literally destroying democracy is just beyond me.. #bluesky 💙

submitted 18 days ago • 2 comments

A little bit of good news: my first paper from work done here @danafarber.bsky.social @harvardchanschool.bsky.social is officially published today in @nature.com Fitting for me that the focus here is ccRCC given my past work dating all the way back to grad school! www.nature.com/articles/s41...

submitted 20 days ago • 3 comments

A new paper on microplastics accumulating in the brain was just published in Nature Medicine. I've reviewed the background and main findings in a new Ground Truths post erictopol.substack.com/p/the-microp...

submitted 22 days ago • 19 comments

Rather than immune suppression, CD206+ TAMs recruit a tumor-reactive network of CD8 T cells, cDC1s, and NK cells doi.org/10.1084/jem.... @maxkrummel.bsky.social @jexpmed.bsky.social

submitted 90 days ago • 0 comments

Big questions about #cancer - discussed in this @nytimes.com article Including risk factors 🏭, new research insights 🧪🔬 and promising treatments ⚕️💊 www.nytimes.com/2025/01/29/w...

submitted 27 days ago • 1 comment

Our February issue is LIVE! 🌟 🤩 It features articles on: - Chromothripsis in cancer - AR signaling in non-prostate cancers - Genetic predisposition to childhood cancers - Long-term adverse effects of childhood cancer therapy https://bit.ly/3E8OM...

submitted 28 days ago • 1 comment

Immunology will be for everyone, everywhere, everyday, from driving foundational research to reaping the benefits for health. 🌎 Immunoschool 2025 is open for anyone looking to learn more about key immunotherapy advances over the last decade. FREE TO REGISTER: www.eventbrite.com/e/internatio...

submitted 28 days ago • 1 comment

January is #MentoringMonth a time to reflect on the importance of mentor-mentee relationships And a good moment to share this beautiful letter written by Albert Camus to his teacher, after receiving the Nobel Prize You can't underestimate the impact of a great #teacher or #mentor! #ThankAMentor 🙏

submitted 29 days ago • 1 comment

🧪 fellow scientists, any advice on a good primer for scRNAseq analysis. Not just the coding part, but the math behind it as well.

submitted 30 days ago • 0 comments

Out now in @natimmunol.bsky.social @meriembelabed.bsky.social & Matthew Park uncover new #CellBiology of DC maturation: cholesterol stores mobilize to stabilize lipid nano-domains in the membrane, enabling immune receptor signaling. 1/2

submitted 35 days ago • 1 comment

A new #ScienceImmunology Review discusses the mechanisms through which dendritic cells influence cytotoxic CD8+ T cell responses against cancer. scim.ag/3PU7hRo

submitted 29 days ago • 3 comments

While this is an interesting piece - there are quite a few issues that have slipped through peer review here: e.g. controlling for heteroplasmy levels in their patient associations (the mutation calls for which are not properly provided in source data) ED Fig 9 @natureportfolio.bsky.social

submitted 33 days ago • 1 comment

Mok et al. evaluated the differences in memory responses between anti-CTLA-4 and anti-PD-1 to better understand why responses to anti-CTLA-4 last longer bit.ly/42oLGrD @mdanderson.bsky.social @jimallisonphd.bsky.social

submitted 34 days ago • 0 comments

How do T cells find the proper instructions to navigate tissues? In the Goldrath Lab @ucsdhealthsci.bsky.social, Amir Ferry mapped it out play-by-play. Potentiating these interactions strengthens the immunity cycle and enhances tumor control 1/n

submitted 34 days ago • 0 comments

New paper alert 📢! (Cell) @cp-cell.bsky.social - How does immune responses to solid tumors vary by age and tumor characteristics in children?! www.cell.com/cell/fulltex... 🧵1/8

submitted 36 days ago • 3 comments

🚨We're hiring! We've opened a fully-funded Ph.D. position to join my lab at the #LIH, if you are interested in understanding how genetic variation influences immune responses against cancer, don't hesitate to apply! 🔬 🧪 More info below ⬇️ www.lih.lu/en/job/?valu... #cancer #immunology #genomics

submitted 36 days ago • 0 comments

Why understanding biology matters in bioinformatics One big lesson: RNA and protein levels aren’t always correlated. If you don’t know this, you might draw the wrong conclusions. 🧵👇

submitted 36 days ago • 8 comments

Looking at bioinformaticians’ profiles these days, you'd think everyone has decades of experience in cutting-edge single-cell and AI-driven bioinformatics. But something’s missing… 👇

submitted 37 days ago • 1 comment

First lab Bluesky post! Happy to share new papers: PRINT: Using Perturb-map, we show in @cellpress.bsky.social how ovarian tumors resist immunotherapy > www.cell.com/cell/abstrac... PREPRINT We developed a new technology to easily generate cell-targeted LNP-RNA > www.biorxiv.org/content/10.1...

submitted 41 days ago • 0 comments

Dive into career journeys of PIs in immunology, from mastering lab techniques, securing tenure, to navigating moves and balancing family with research🧗 Based on @yefis-immunology.bsky.social ECR workshop at #ECI2024 A must-read for aspiring immunologists and ECRs!👉 bit.ly/4fXeUkC

submitted 42 days ago • 1 comment

Hot off the press 🔥 Very proud of this collaboration! 💫 @Harvard @JohnsHopkins @UChicago @UniHeidelberg Interested in immunotherapy-induced toxicity? 🤓 This is a must-read 🤩 #immunology #science #cancer #research @nct-heidelberg.bsky.social @dkfz.bsky.social www.cell.com/trends/immun...

submitted 60 days ago • 1 comment

Cancer Cell is now on this side of the web! We hope you join us and continue to engage with us to help us develop a strong network based on our common interest of publishing impactful and cutting-edge cancer papers across the basic, translational, and clinical spaces.

submitted 43 days ago • 0 comments

Happy to share our last review on TAMs complexity! Mastered by @saraimrtnez.bsky.social & #janHochstadt from @cniostopcancer.bsky.social check it out: www.sciencedirect.com/science/arti...

submitted 54 days ago • 2 comments

Yet another reason why, in translational immuno-oncology, models are limited and human work must be done in parallel: An astounding 60% homology difference in PD-1 from rodent to human! www.science.org/doi/10.1126/...

submitted 43 days ago • 0 comments

Precursors of exhausted T cells are preemptively formed in acute infection At that stage early precursors show diversity; memory T cells but also cells with a phenotype, gene-expression, and epigenetic profile that resembles precursors of exhausted T cells. #ImmunoSky www.nature.com/artic... 1/3

submitted 48 days ago • 1 comment

You cannot underestimate all the positive and long-term benefits of having a supportive #mentor One could argue this is at least as important as the research topic 🧪 Do choose wisely.. #MentoringMonth

submitted 49 days ago • 2 comments

5,562 proteins were found to have tissue-specific enrichment across 32 human tissues. The majority of them (3,088) are enriched at the protein but not RNA level. The brain hosts the largest number of proteins that are only enriched at the protein level but not RNA level.

submitted 49 days ago • 3 comments

There's a really interesting new paper out in Science for people who care about immunity to flu (which should be everyone because flu is a VERY big problem): www.science.org/doi/10.1126/... Here's my thread explaining this work🧵

submitted 67 days ago • 10 comments

We've just joined Bluesky 🎉 Follow us for research, news, comment and opinion from Nature journal 🧪

submitted 68 days ago • 36 comments

We are hiring! #MANIFESTuk 3 more positions now open: 💻 Postdoctoral Fellow – Computational Modelling 🧬 Senior Bioinformatician (Genomics) 🔬 Senior Bioinformatician (Imaging) @manifest-cirrp.bsky.social @crick.ac.uk Check out below for more info 👇

submitted 68 days ago • 1 comment

Today #preprinthub2 Tamina and Joel will present a #preprint from @miriammerad.bsky.social @samhegde.bsky.social @sinaiimmuno.bsky.social on how myeloid progenitor dysregulation fuels immunosuppressive #macrophages in tumors ✍️💥 🥸👇 www.biorxiv.org/content/10.1...

submitted 71 days ago • 0 comments

Spatial transcriptomic clocks reveal cell proximity effects in brain ageing 🧠 🕙 Incredible study 🧪 in Nature from @brunetlab.bsky.social and the Zou lab 🎉 So many intriguing findings - including that T cells have a pro-ageing proximity effect on neighbouring cells 🤯 @natureportfolio.bsky.social

submitted 69 days ago • 1 comment

Our December issue is LIVE! 🚨🎄❄️ It features Reviews on: - Cancer induced pre-conditioning of distant organs, - Strategies to investigate the biology of early cancer, - Precursor multiple myeloma - & a #Roadmap on mRNA splicing in the clinic bit.ly/4i3cnaG

submitted 69 days ago • 0 comments

One of the biggest questions we get is when will our journals be here. We thank you for your patience. You can now follow our journals with this starter pack!

submitted 70 days ago • 20 comments

How does the immune system make "decisions" at mucosal barriers? My new perspective explores how seeing strategic cell interactions through the lens of game theory could reveal fresh insights into mucosal immune homeostasis and disease. 🧵 1/7 www.sciencedirect.com/science/arti...

submitted 73 days ago • 4 comments

Immunity wanes with advanced age in humans and mice, but recent research from Singh et al. shows that Rab8a-reconstitution may restore youthful functions in aged DCs, enhancing immune protection. bit.ly/3ZtiSuZ

submitted 76 days ago • 0 comments

Isshiki et al. developed syngeneic mouse models of FL and DLBCL to study inhibitors of the histone methyl-transferase enhancer of zeste 2 (EZH2), which mediates broad gene silencing, mostly by targeting tumor suppressor genes. acir.org/journal-art... @cornelluniversity.bsky.social

submitted 75 days ago • 0 comments

This platform keeps getting better and better! 😍🦋 The @preprintclub.bsky.social joined the bright side. #immunosky Share and follow for inter-institutional, trainee community reviews of preprint articles. #preprints #openacess www.preprintclub.com

submitted 77 days ago • 2 comments

Really happy to share our new publication! @anna-vaharautio.bsky.social Stay tuned for more insights! @farkkilab.bsky.social www.helsinki.fi/en/news/canc...

submitted 78 days ago • 0 comments

Are you an #Immunologist? Do you have expertise in #MolecularBiology and #CellBiology? Do you want to investigate why men and women mount immune responses differently? Join us as a #PostDoc in #SystemsImmunology and explore mechanisms of #SexDifferences in #Immunity! See more below (please RT)

submitted 78 days ago • 0 comments

#NatureReviewsCancer 🚨 Genetic predisposition is a known cause of childhood cancers. In this #Review, Christian Kratz highlights #cancerpredisposition syndromes + genes, focusing on the associated risks & the clinical implications to improve patient care. bit.ly/3ZHhZAA

submitted 83 days ago • 0 comments

Excited to share our perspective on genetic immune escape alterations and their impact on tumor evolution, metastasis, immunotherapy, and interactions with tumor-extrinsic factors. It was a pleasure collaborating with Diego on this -hope you enjoy the read!☺️ www.sciencedirect.com/science/arti...

submitted 83 days ago • 1 comment

Out today: Oncolytic Virotherapy Plus Nivolumab Is Safe in Muscle-Invasive #BladderCancer, a #ResearchWatch summary of recent clinical findings by Roger Li, James J. Mulé, Jose R. Conejo-Garcia, and colleagues. aacrjournals.org/cdnews/news/...

submitted 83 days ago • 0 comments

What were the most inspiring 2024 discoveries in cancer? Cancer Discovery asked me, Katherine Aird, Aadel Chaudhuri, Jennifer Guerriero, Shiri Gur-Cohen, Benjamin Izar, Brittany Jenkins, Delphine Merino, Alejo Rodriguez-Fraticelli & Shensi Shen, & here's what we said aacrjournals.org/cancerdiscov...

submitted 84 days ago • 1 comment

“Anyone can cook, but only the fearless can be a great chef” I discussed my vision on how anyone can run a lab but fearless will succeed I really enjoyed writing this piece commissioned by @labliston.bsky.social at #immunology&CellBiology onlinelibrary.wiley.com/doi/10.1111/...

submitted 85 days ago • 1 comment

We’re looking for a PhD student in brain onco-immunology! Apply here, one week to go: kidoktorand.varbi.com/en/what:job/...

submitted 87 days ago • 1 comment

🔔 New publication alert : have you ever wondered whether #immune and #tumor cells use similar mechanisms to #extravasate ? Do they indoctrinate the #endothelium ? We did. Awesome work by Amandine & Naël. Check it out : journals.biologists.com/jcs/article-... Published in @biologists.bsky.social

submitted 100 days ago • 1 comment

1/23 Big news for the #ObenaufLab! So excited to finally share our new study providing another puzzle piece, why immunotherapy fails in many tumors, now out in @Nature 🧵👇 www.nature.com/articles/s41...

submitted 90 days ago • 49 comments