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mRNA Vaccine for Pancreatic Cancer. If this works, it's going to be huge. www.nature.com/articles/s41...

submitted 2 days ago • 0 comments

A region of Texas reflexively against anything that they perceive to impinge on their "personal liberty." Or, to put it another way, not very good at collective security/safety. A reminder: measles is one of the most contagious viruses. www.dshs.texas.gov/news-alerts/...

submitted 5 days ago • 0 comments

submitted 5 days ago • 1 comment

THIS IS HUGE! Researchers at Memorial Sloan Kettering Cancer Center say results of a Phase I trial of an mRNA vaccine aimed at preventing pancreatic cancer show promise. The vaccine PREVENTED the cancer from coming back in patients who had already received treatment for MORE THAN three years. 🧪🧵⬇️

submitted 8 days ago • 349 comments

Occam's Razor suggests that these guys are either the dumbest people who ever lived, or that they actively want to destroy the United States, or both.

submitted 7 days ago • 6 comments

TOP DEM POLLSTER: The more New Yorkers learn about the MONSTER that is ANDREW CUOMO the less they will accept him as their mayor. So many of us New Yorkers are ready to show who he is. An abuser. A liar. A crook who constantly helps himself at the expense of New Yorkers. t.co/REla7UwBrn

submitted 8 days ago • 17 comments

DOGE By The Numbers theonion.com/doge-by...

submitted 8 days ago • 187 comments

Pangolins are out, Racoons are in… www.nature.com/articles/d41...

submitted 7 days ago • 0 comments

New: DOGE's spending has been secret. No longer. My colleagues have uncovered it. www.propublica.org/article/doge...

submitted 8 days ago • 861 comments

It is gratifying to see that the physician who diagnosed this pilot as bipolar, based on academic and maternal skills, has removed himself from caring for patients. Whoring for attorneys in litigation is one of the uglier sides of contemporary medicine.

submitted 8 days ago • 0 comments

Could be a huge addition to cancer immunotherapy or vaccine “design.” Such proteins, if sufficiently different from native proteins would totally overwhelm cancer cells natural adaptive strategies. Same for viral or bacterial pathogens. www.sciencemagazinedigital.org/sciencemagaz...

submitted 8 days ago • 0 comments

NEW: Pregnancy became far more dangerous in Texas after the state banned abortion, according to ProPublica’s first-of-its-kind analysis, which found the sepsis rate for women hospitalized as they miscarried in the 2nd trimester shot up by more than 50%. https://propub.li/43487Tj

submitted 9 days ago • 563 comments

Ruhle: The left-leaning podcast MeidasTouch has just done the unthinkable—dethroned Joe Rogan to become the country’s most popular podcast…

submitted 9 days ago • 1035 comments

Retrospective study. Early pancreatic cancer detection. What is needed, next, is a similar system for Esophageal Cancer, albeit much harder to find distinct proteins in that cancer but maybe MI-RNA. www.nature.com/articles/d41...

submitted 9 days ago • 0 comments

’Tis the time’s plague, when madmen lead the blind.

submitted 11 days ago • 14 comments

RFK Jr. thinks that a clinical trial should be done for the entire childhood vaccine schedule. Here’s why that will never happen. 1. You can’t do a randomized trial of something that we already know is safe and effective. There would have to be a placebo group that didn’t get vaxxed. Unethical.

submitted 10 days ago • 697 comments

Math is hard

submitted 10 days ago • 2024 comments

Amen. Every update to my iPhone OS produces more dancing Emojiis but less simple referential functions that are useful in everyday work.

submitted 10 days ago • 0 comments

CAR-T cells can arm other immune cells with engineered proteins to fight cancer, study says www.statnews.com/2025/01/31/c... via @statnews.com Commensalism among microbes is increasingly appreciated, and now a very convenient example in human Car-T cells that transfer anti-cancer activity.

submitted 10 days ago • 0 comments

For folks in DC with animal pals

submitted 11 days ago • 106 comments

Pancreatic cancer: blocked nerves as a possible new treatment strategy - German Cancer Research Center

submitted 11 days ago • 0 comments

Today in WTF Facebook Marketplace we have…a rock. Trust me on this one. I’m an archaeologist and that is a rock. A totally natural rock. But at least it’s $1500 off the initial price! 2 pictures this time so you can fully appreciate the nutty description and…rockness.

submitted 15 days ago • 8 comments

ATTN HHS EMPLOYEES: Firing notices are going out. I am in receipt of an email saying they will revoke your access as soon as you read the email that you've been fired. Please download everything you need before you open that email. SHARE FAR & WIDE. My latest: www.muellershewrote.com/p/attn-hhs-e...

submitted 14 days ago • 451 comments

www.quantamagazine.org/the-largest-...

submitted 14 days ago • 0 comments

BREAKING On Monday, Popular Information broke the news that the NIH had frozen virtually all grant funding in violation of 2 federal court orders On Wednesday, NIH leadership distributed a memo, acknowledging that its funding freeze was illegal and directing staff to resume issuing grants.

submitted 16 days ago • 373 comments

Wut

submitted 18 days ago • 0 comments

BREAKING: VIRUS FROM NEVADA DAIRY WORKER WITH BIRD FLU HAS THE SAME GENETIC MUTATION seen in the Nevada cows – a change of PB2 D701N that has previously been assoc with more efficient virus replication in ppl & mammals. CDC told Fortune that the D1.1 variant in this worker is the same strain of

submitted 18 days ago • 473 comments

Mapping death, hospitalizations, and case levels against vaccination prevalence factored against Documented, objective vaccine complications could make West Texas finally socially useful in some future debate about the value of childhood vaccines. Historically 20% hospitalized, .3% die.

submitted 18 days ago • 0 comments

Think the military lowered its standards for women? Think again.

submitted 18 days ago • 0 comments

Whenever you hear someone sneer about scientific research that seems useless to them — “they’re studying the spit of lizards?!” — remind them that’s exactly how we got Ozempic. globalnews.ca/news/9793403...

submitted 20 days ago • 527 comments

This is a second post looking at Evangelism and death rates, this measure is life expectancy, the age by which half the people die. I am focusing on Evan and death rates because Trump has put Evans in charge of health care. They got rid of research because they use prayers for health care? 🧪☠️

submitted 19 days ago • 9 comments

Alternative to traditional small molecule antibiotics for multi- drug resistant bacteria: photodynamic inactivation. engineering.tamu.edu/news/2025/01...

submitted 19 days ago • 0 comments

www.quantamagazine.org/how-noethers...

submitted 21 days ago • 0 comments

“...to care is an act not of weakness, but of strength.” The Lancet response: bit.ly/4jRb5Av

submitted 22 days ago • 15 comments

A rare re-post from X/Twitter, a substantial adjunct to protein folding software…protein localization. x.com/samuelbhume/...

submitted 22 days ago • 0 comments

Promising results for therapy targeted at the BRAF-mutant subtype of colorectal cancer. www.nature.com/articles/s41...

submitted 22 days ago • 0 comments

The Philadelphia Eagles’ offensive line is historically large—and they’re out to flatten the Kansas City Chiefs. Pro football may be reaching an asymptotic limit of size and weight. On display at this years Super Bowl Philli linemen.

submitted 23 days ago • 1 comment

A key gut mucous layer bacteria is now better characterized at at the enzyme- function level. This commensalism is key to sustaining gut health, and in turn, preventing gut boundary leakage, dysbiosis, and glucose levels, hence a key positive player in DM2 and IBD. www.nature.com/articles/s41...

submitted 26 days ago • 0 comments

The gut is increasingly linked to systematic immunity and consequential diseases of the immune system. Mapping immune cell specialization and regionalization is helpful if not essential. alleninstitute.org/news/new-res...

submitted 37 days ago • 0 comments

Snake envenomation kills 100,000 people per year. WHO recognizes this stat as neglected tropical disease. Now , along comes AI protein design for an of-the-bench antivenin. www.nature.com/articles/d41...

submitted 37 days ago • 0 comments

10 days until I'm officially no longer unemployed. Not enough time to do something sensible with, but enough time to do something stupid with.

submitted 43 days ago • 0 comments

www.sciencemagazinedigital.org/sciencemagaz... Haptic feedback and control remains one of the major challenges for robotics and advanced limb prosthetics. 25 years ago I funded work to just get a robot not to crush a glass with a grasper. Research has come along way as this report documents.

submitted 43 days ago • 0 comments

Vaccine design remains a non-deterministic science. AI may change that. www.nature.com/articles/d41...

submitted 44 days ago • 0 comments

As an anatomist anything about the Vagus nerve interests me and there are some tidbits in this article. BUT, it's the comments that are 🔥. #ITeachAnatomy #AnatomyEdu 🧪

submitted 45 days ago • 1 comment

"I feel like I am safe in saying that we are not thriving on our changing planet. And we won’t thrive on our changing planet in the coming decades." - JPL climate scientist Ben Hamlington, lead of the NASA Sea Level Change Team, whose house in Altadena was destroyed by the fossil-fueled #EatonFire.

submitted 45 days ago • 2 comments

It's not just the change, but the variability and unpredictability. www.theguardian.com/environment/...

submitted 44 days ago • 2 comments

In-vivo gene excision and replacement in an infant. iecure.com/news/iecure-...?

submitted 45 days ago • 0 comments