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westberglab.com
Assistant Professor at Aarhus University, Denmark | biophysical chemistry PhD | into chembio, synbio, protein design, photochem, microscopy | 2018-2022 at Stanford Bio-X | westberglab.com
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Posts 14 Comments 6

Instruktøren for kryolit-dokumentaren tager til genmæle i P1 Orientering - men svarene er langt fra overbevisende: www.dr.dk/lyd/p1/p1-or... For mig at se er dokumentaren et eksempel på misinformation, som det oftest praksiseres i politik og på sociale medier. 🧵 (1/4)

submitted 15 days ago • 3 comments

Excited to share our latest preprint evaluating AlphaFold3, Boltz-1, Chai-1 and Protenix for predicting protein-ligand interactions, featuring our newly introduced benchmark dataset 🌹Runs N’ Poses🌹! www.biorxiv.org/content/10.1... 🧵👇 (1/n)

submitted 18 days ago • 4 comments

Special Bluetorial: The benefits of different life experiences The scientific community has folks with a very wide range of life experiences. We have a lot to learn from one another.

submitted 19 days ago • 4 comments

New preprint from our group! We propose SHAPES, a set of metrics to quantify the distributional coverage of generative models of protein structures with embeddings at different structural hierarchies and quantify undersampling / extrapolation behaviors.

submitted 42 days ago • 1 comment

Yes it's important people understand a preprint hasn't been peer-reviewed. BUT it's also important to understand that what "peer-reviewed" means varies considerably, in some cases signifying nothing... www.science.org/content/arti...

submitted 49 days ago • 8 comments

Many people talk about the "Golden Age of Antibiotics", but I hadn't seen it visualized properly. Just how many types of antibiotics were discovered during that time? So, I visualized it myself!

submitted 65 days ago • 24 comments

1/ In two back-to-back papers, we present our de novo TRACeR platform for targeting MHC-I and MHC-II antigens TRACeR for MHC-I: go.nature.com/4gcLzn5 TRACeR for MHC-II: go.nature.com/4gj5OQk

submitted 71 days ago • 2 comments

Back by popular demand, I present PPI Prediction Challenge #2. My claim: I AM SKEPTICAL COMPUTATIONAL APPROACHES CAN PREDICT WHETHER TWO PROTEINS INTERACT. Someone prove me wrong (take two). docs.google.com/forms/d/e/1F... 1/n

submitted 78 days ago • 4 comments

You may have seen a recent pre-print [1] from Jain et al. with strongly worded claims against the experimental results in our DiffDock paper [2]. We initially declined to respond as we saw that this preprint contained falsehoods, misleading comparisons, seemingly deliberate omissions, ...1/n

submitted 80 days ago • 2 comments

Super excited to preprint our work on developing a Biomolecular Emulator (BioEmu): Scalable emulation of protein equilibrium ensembles with generative deep learning from @msftresearch.bsky.social ch AI for Science. www.biorxiv.org/content/10.1...

submitted 82 days ago • 22 comments

Hey @biorxivpreprint.bsky.social, I think you need to add another icon here 🦋

submitted 96 days ago • 1 comment

PIONEERS When I assumed the position as Director of NIGMS in 2003, Dr. Zerhouni's project for stimulating activities across NIH, The NIH Roadmap for Medical Research, was under active development. The Roadmap included a range of different funding opportunities. 1/n www.science.org/content/arti...

submitted 96 days ago • 1 comment

We engineered bacteriorhodopsin to be soluble. It binds retinal and can photocycle! X-ray structure reveals conserved binding pocket with 0.8 Å all atom RMSD to WT BR. All this became possible due to hard work by Andrey Nikolaev and the team 🙏 #proteindesign biorxiv.org/cgi/content/...

submitted 96 days ago • 8 comments

Crosspost from X: After showing that AF2 can be used to design very large proteins by performing #RSO, I am happy to share another fun project we did: the #af2cycler @sokrypton.org @hendrikdietz.bsky.social www.biorxiv.org/content/10.1...

submitted 96 days ago • 1 comment