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xaviertrepat.bsky.social
Scientist of Living Matter. ICREA Professor at the Institute for Bioengineering of Catalonia, Barcelona. The need to know.
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1/7: New paper alert! Excited to share our co-first author paper on Micro Immune Response On-chip (MIRO) a model that recreates the tumour-stroma interface for immunotherapy testing! @oriolmb.bsky.social and I wrote this thread to break it down for you. 👇🧵 Read more: www.nature.com/articles/s41...

submitted 16 days ago • 1 comment

New paper from the lab🎈. Introducing Micro Immune Response On-chip (MIRO), a device that replicates tumors and their microenvironment to better understand responses to immunotherapies (cyan=immune cells, red=cancer, green=CAFs). www.nature.com/articles/s41... @ibecbarcelona.eu

submitted 19 days ago • 7 comments

How do epithelial tissues develop their diverse, beautiful shapes? Some researchers have been controlling their forces with light to understand it. I’m Guillermo Martínez Ara and today I’ll tell you about how we can use optogenetics to study morphogenesis!

submitted 25 days ago • 1 comment

Can we construct mathematical models for psychology? Can phase transitions help understand critical changes in psycho-social systems? Check this fascinating @sfiscience.bsky.social talk by Han van der Maas, youtube.com/watch?v=eujJ...

submitted 48 days ago • 0 comments

Our latest: how to generate the notochord "Timely TGFβ signalling inhibition induces notochord" A thread: www.nature.com/articles/s41...

submitted 69 days ago • 7 comments

Mechanics of cell extrusion unlike anything seen before in epithelia. If you are at ASCB #CellBio2024 don’t miss Marija’s talk on organoid mechanobiology.

submitted 72 days ago • 0 comments

After five decades of outstanding science and mentorship, Jeff Fredberg is retiring. Today, we gather in Boston to celebrate his career. A truly special day for all of us who had the privilege of growing under his leadership!

submitted 74 days ago • 0 comments

👋Hello #mechanobiology community in 🦋! This is the official account of the 10th Edition of the Cell Mech conference! 🔧We will soon announce the invited speaker list! Visit our website, subscribe to the mailing list, and follow us!: cellmech2025.org 😍Join us in Leuven 2025!

submitted 78 days ago • 1 comment

A thread on our recent preprint👇👇👇

submitted 83 days ago • 0 comments

The IOP Mechanobiology meeting starts strong with @johannaivaska.bsky.social telling us that cells do not necessarily migrate towards stiff and that nuclear YAP does not necessarily correlate with cell spreading. 💪

submitted 84 days ago • 2 comments

🎈New preprint! We study how single cells move up, down and about fibronectin gradients. Experiments by @icfortunato.bsky.social, theory by David Bruckner. Collaboration with @raimonsunyer.bsky.social and @ehannezo.bsky.social 👇https://biorxiv.org/cgi/content/short/2024.12.02.626413v1

submitted 85 days ago • 5 comments

Let’s understand collective cell migration by breaking it down to its essential elements! I'm Leone Rossetti, and this is a thread showcasing what we can learn from cells journeying along narrow paths, and from the forces they generate. 1/ #EpithelialMechanics

submitted 87 days ago • 2 comments

Mix two motors of opposite polarity with microtubules and they will partition space ! Microtubules will get organized in polar and active barriers, sorting the two motors in separated domains, leading to the emergence of a new type of patterns. #morphogenesis doi.org/10.1073/pnas... (1/n)

submitted 91 days ago • 8 comments

Next week in London: Mechanobiology Shaping Life. The deadline for registration is tomorrow, 26/11. iop.eventsair.com/msl2025/

submitted 93 days ago • 0 comments

I am delighted to share our new preprint in which we reveal the crucial role for mechanical forces in myoblast fusion. Great work from Yoann, Sushil and Aleksandra and great collaboration with Christophe Marcelle and Amin Doostmohammadi! www.biorxiv.org/content/10.1...

submitted 94 days ago • 3 comments

And they should all be equipped with a blackboard like those at the Erwin Schrödinger Institute in Vienna (couldn’t help taking a picture 😅). #BringYourOwnChalk

submitted 96 days ago • 2 comments

Pre-announcing the EMBO/EMBL symposium "Mechanobiology Across the Tree of Life", Heidelberg, 9-12 June 2026. It is still very very far away, but save the date 🗓️. With Alba Diz-Munoz, @nicolettapetridou.bsky.social , Kirsty Wan @micromotility.bsky.social, Enrique Rojas. www.embl.org/about/info/c...

submitted 98 days ago • 4 comments

Wonderful threat on Traction Force Microscopy by the EMFC! Incidentally, it should be called Traction Microscopy, without ‘Force’, because it measures tractions and not forces. I tried to push for this change for some time, but quickly gave up.

submitted 101 days ago • 2 comments

A couple of recent multi-author perspectives on the present and future of physical biology. www.sciencedirect.com/science/arti... www.cell.com/current-biol...

submitted 102 days ago • 1 comment

Introducing "3D Micropatterned Traction Force Microscopy", our new joint work with Pere Roca-Cusach's lab, led by amazing Laura Faure and Manu Gómez. Hope you find it useful!👇 onlinelibrary.wiley.com/doi/full/10....

submitted 103 days ago • 2 comments