Happy to see my Postdoc work out @natbiotech.nature.com. Using HaloTag and synthetic fluorophores instead of FPs enables us to shift the spectral properties of kinase activity reporters (KARs) to the far-red π¬. Huge thanks to everyone involved @jinzhanglab.bsky.social!
https://www.nature.com/articles/s41587-025-02642-8
https://www.nature.com/articles/s41587-025-02642-8
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Also grateful to @anne-lyons-bioe.bsky.social for all the help with super-res image analysis!