kriyer.bsky.social - Profile | ThreadSky | a Reddit-style client for Bluesky

Vaccines don’t cause autism. Vaccine ingredients don’t cause autism. Vaccines don’t worsen autism symptoms. Millions of data points over decades show this. A paper published in a “journal” that funded the “study” doesn’t supersede reality. Stop spreading lies that harm people. 1/

submitted 40 days ago • 5 comments

www.sciencedirect.com/science/arti... Link to the paper that should help everyone diagnose keratoacanthoma with greater confidence.

submitted 53 days ago • 0 comments

pubmed.ncbi.nlm.nih.gov/33742141/ #pathsky

submitted 56 days ago • 0 comments

#PathSky It’s interesting how we discover things sometimes. On this particular Sunday, I got an email from an Ortho Onc asking what a JXG was. “Just a benign skin tumor.” “Well, this is deep and eroding bone.” “Erm, let me look at it…” Mostly looks like JXG, but what are those eosinophilic cells?

submitted 72 days ago • 1 comment

#PathSky 67F, s/p lumpectomy and RT 5 yrs ago for DCIS, now with a mass IN the breast. The outside was worried about post RT angiosarcoma, in part because of the CD31 and C-MYC. This is just fat necrosis with CD31-pos macrophages. 1- post RTAS occurs in the SKIN, not breast. 2- macs express CD31.

submitted 71 days ago • 1 comment

Super little finding. Patient presented with abdominal pain. Here’s a gastric biopsy… #pathsky #pathology #GIPathology #histology #histopathology

submitted 62 days ago • 2 comments

Fun, incidental findings. Liver hemangioma with extramedullary hematopoiesis (yellow polygon) - mostly megas and erythroids, not a lot of grans in this case. Double bonus finding - erythrophagocytosis (yellow arrows). #PathSky #HemePath

submitted 64 days ago • 0 comments

#PathSky 32M with extra-axial, dural-based, frontoparietal mass. Clearly malignant epithelioid cells arranged in cords and nests in a sclerotic background. Looks a lot like a sclerosing epithelioid fibrosarcoma, and it is strongly MUC4-positive. So, we’re done, right?

submitted 59 days ago • 3 comments

This is a duodenal mass is a patient with inflammatory bowel disease presenting with 1 week of nausea and vomiting. What IHC do you want to order? #pathsky #pathology #histology

submitted 60 days ago • 1 comment

#PathSky Having returned from vacation…Back mass, 17 month M. Looks like a smooth muscle tumor, but infants don’t really get true smooth muscle tumors. And some parts look a bit more primitive. Leiomyosarcoma? Something else?

submitted 61 days ago • 1 comment

One for the New Year! A nice example of lamellar fibrosis which is the papillary dermal hallmark of a dysplastic naevus - this one shows high grade dysplasia. Hope y’all are having a good 2025 so far! 😉💚 #PathSky

submitted 57 days ago • 1 comment

50 + year old male. Large lung tumor. #science #medsky #pathsky #lungpath #lungsky

submitted 65 days ago • 1 comment

Macroscopy, or grossing, is hard work, and it's important. In the first image, we see a big, loosely lobulated, and shiny gelatinous mass. The second image shows adipocytes of varying sizes in a pink, myxoid background with adjacent chicken wire-like vessels. This is myxoid liposarcoma. #PathSky

submitted 65 days ago • 0 comments

Jumping into 2025 with an endolymphatic sac tumor, a VHL-associated neoplasm arising in the posterior petrous bone of the ear #pathsky #eqbsky #neuropath #entpath

submitted 65 days ago • 5 comments

Snow in Boston! Sharing a crazy "snowflake-like" mitosis in this megakaryocyte. Looking forward to being more active on this platform in the new year! #pathology #hemepath

submitted 78 days ago • 0 comments

#PathSky 15F, thumb mass. There are no relevant positive immunostains. However, FISH for DDIT3 amplification (not rearrangement) is positive. This is an excellent example of a GLI1-amplified sarcoma. This is a great paper from the MSKCC group. pubmed.ncbi.nlm.nih.gov/38934567/

submitted 78 days ago • 1 comment

#PathSky Since I was on vacation, here’s one more. 47M, arm mass. Don’t overthink it- it’s just an undifferentiated pleomorphic sarcoma. But- the outside was concerned for LMS, because of the diffusely positive caldesmon. Oddly, all the other muscle markers were negative. Can you explain this?

submitted 78 days ago • 1 comment

⚕️ 𝗧𝗵𝗼𝗿𝗮𝗰𝗶𝗰 𝗦𝗠𝗔𝗥𝗖𝗔𝟰-𝗗𝗲𝗳𝗶𝗰𝗶𝗲𝗻𝘁 𝗨𝗻𝗱𝗶𝗳𝗳𝗲𝗿𝗲𝗻𝘁𝗶𝗮𝘁𝗲𝗱 𝗧𝘂𝗺𝗼𝘂𝗿 (𝗦𝗗𝗨𝗧)⚕️ As discussion below: www.linkedin.com/posts/trista... #Pathtwitter #Pulmpath #BSTpath

submitted 81 days ago • 0 comments

#slidearchiveseries metastatic mixed germ cell tumor (teratoma and choriocarcinoma) involving lymph node #gupath #pathsky 🏥 h/o testicular mixed germ cell tumor (teratoma, choriocarcinoma, seminoma) s/p chemotherapy and RPLND with growing mediastinal mass and increasing HCG

submitted 86 days ago • 0 comments

Always keep 👀s open when scanning breast cores with columnar cell change for intruders 😉 📸1 Columnar lining with >2 layers 📸2 Vacuolated 3rd population 📸3 E-cadherin #InsituLobularNeoplasia #pathology #breastpath #pathsky 🤓

submitted 85 days ago • 0 comments

#slidearchiveseries SMARCB1 deficient renal medullary carcinoma #gupath #pathsky #pathoutpic 🩸 young pts with sickle cell trait 🔬 cribriform, reticular, nested growth 🎨 PAX8, broad spectrum CKs, CEA, p53 ⚠️ OCT3/4 ➕ (50%), pitfall with GCT 🔑 SMARCB1 / INI1 inactivation

submitted 86 days ago • 1 comment

Great example of a classic #ENTPath / #OralPath diagnosis. #PathSky

submitted 86 days ago • 2 comments

Just learned about bluesky! For a first post, here is an image of ductal type prostate cancer. Diagnostic criteria can be controversial but common features are columnar cells and papillary structures. Typically considered grade 4. #GUpath

submitted 86 days ago • 2 comments

#slidearchiveseries embryonal carcinoma #gupath #pathsky 🔬 pseudoendodermal sinus-like 🎨 OCT4 📑 pubmed.ncbi.nlm.nih.gov/29129333/ 🏥 history of epididymo-orchitis; enlarged testicle with a heterogeneous mass-like area (increasing in size), serum tumor markers not known

submitted 86 days ago • 0 comments

#slidearchiveseries clear cell adenocarcinoma of urinary bladder #gupath #pathsky 🔬solid, tubulocystic, and papillary growth patterns; hobnail cells with eosinophilic or clear cytoplasm ➕ CK7, PAX8, HNF1β, p53, Napsin ➖ GATA3, p63, ER, PR, WT1

submitted 86 days ago • 0 comments

A potential pitfall! #Yikes #SclerosingAdenosis mimicking #LobularCarcinoma Always 👀 for myoepithelial cells which may have vacuolated cytoplasm. The last 📸 is smooth muscle actin. #pathology #pathsky 😎

submitted 86 days ago • 0 comments

#slidearchiveseries urothelial carcinoma, plasmacytoid variant #gupath #pathsky #pathoutpic 🔬discohesive single tumor cells, eccentrically placed nuclei, eosinophilic cytoplasm 💥high grade, poor prognosis 🙅🏻‍♀️do not use CD138 in isolation to distinguish from plasma cells

submitted 86 days ago • 0 comments

#macrovsmicro radical orchiectomy, gray-white to red-brown, heterogeneous, focally hemorrhagic and focally degenerative mass #gupath #pathsky #testicularcancer

submitted 86 days ago • 2 comments

Today’s case for #dermpath learning #SquamoidEccrineDuctalCarcinoma 🔬Infiltrative architecture 🔬Squamous islands with pores intermixed with #syringoma like tubules 🔬4 #PerineuralInvasion 🎓Recurrence risk but no mets 🤓 #pathology #dermatology #pathsky

submitted 88 days ago • 0 comments

#slidearchiveseries nephrogenic adenoma #gupath #pathsky #pathoutpic 🏥 prior urothelial injury (surgery, calculi, trauma) sites: bladder > urethra > ureter 🔬 metaplastic lesion, multiple morphological patterns 🎨 PAX8, AMACR, GATA3 (40%), PSA (weak) (+) ⚠️ exclude prostate & bladder ca

submitted 86 days ago • 0 comments

#slidearchiveseries papillary renal neoplasm with reverse polarity #gupath #pathsky #pathoutpic 🕵🏻‍♀️ usually asymptomatic, incidentally found, clinically indolent 🔬 thin papillary/tubulopapillary growth, apically located, low grade nuclei 🎨 CK7, GATA3, L1CAM 🧬 KRAS mutation

submitted 86 days ago • 0 comments

#macrovsmicro gray-white, fleshy to whorled, focally hemorrhagic and bosselated paratesticular mass #gupath #BSTpath #pathsky #pathoutpic

submitted 86 days ago • 1 comment

#slidearchiveseries scrotal calcinosis #gupath #dermpath #pathsky #pathoutpic 🔬intradermal nodules varying in size and number, foreign body giant cell reaction in surrounding tissue 📊 differentials include calcification of epidermal or pilar cyst 🤔 idiopathic or dystrophic

submitted 86 days ago • 0 comments

Good morning #bluesky. Here’s the prettiest Arias-Stella reaction I’ve ever seen 🤩. #pathsky #pathart #pathology #gynpath

submitted 88 days ago • 2 comments

Some basic pointers on how to diagnose a classic case of metastatic melanoma

submitted 88 days ago • 0 comments