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Learn about T-Cell exhaustion in Long COVID with Professor David Putrino. longcovidtheanswers.com #longcovid #longhauler @putrino_lab @polybiorf.bsky.social www.youtube.com/shorts/MQ31V...

submitted 56 days ago • 1 comment

"LC patients displayed persistent immune alterations, including reduced T cell subsets (CD4, CD8, Tregs) and switched memory B cells, similar to COVID-19 patients." pubmed.ncbi.nlm.nih.gov/39845978/

submitted 38 days ago • 0 comments

Long COVID manifests with T cell dysregulation, inflammation and an uncoordinated adaptive immune response to SARS-CoV-2 | Nature Immunology Tja da müssen mir die Psychosomatik Fanatiker mal erläutern wie das geht und warum das Mild ist www.nature.com/articles/s41...

submitted 37 days ago • 2 comments

The JN.1 variant of SARS-CoV-2 resulted in a major Covid wave a year ago. A new report uncovers T cell immune evasion as a mechanistic basis. We've been preoccupied on neutralizing antibodies, not enough on cell-based immunity to the virus. www.nature.com/articles/s41...

submitted 33 days ago • 6 comments

1 - There's SARS persistence in renal epithelium cells beyond the acute phase where the resulting inflammation depletes host immunity. #MedSky #LongCOVID is #AirborneAIDS so #WearN95 www.frontiersin.org/journals/imm...

submitted 16 days ago • 1 comment

All informed people know that SARS-CoV-2 can harm your immune system, even in mild cases of COVID-19. Research has shown that the virus can cause long-term changes and damage to various components of your immune system.

submitted 20 days ago • 1 comment

People with diabetes have weaker, shorter-lived T cell responses to COVID-19 vaccines. Their immune memory fades faster, and booster shots trigger a tolerogenic, anti-inflammatory response instead of strong protection. www.biorxiv.org/content/10.1...

submitted 19 days ago • 0 comments

New Lancet study shows extremely low, 2%, recovery rate from Long COVID. However, those who considered their Long COVID resolved were still in worse health than those who never had Long COVID. www.thelancet.com/journals/lan...

submitted 10 days ago • 12 comments

“The majority of those with Long COVID did not resolve, with less than 2% having resolved Long COVID. The resolved Long COVID cohort had moderately worse physical and mental health compared with those never-having-Long COVID.” www.thelancet.com/journals/lan...

submitted 10 days ago • 5 comments

Medscape: 'New Five-Type Index Provides Doctors Guide for Long COVID' The new five-type index, developed by federal researchers with the National Institutes of Health’s RECOVER COVID Initiative, identified the most common symptoms in 14,000 people with long COVID www.medscape.com/viewarticle/...

submitted 10 days ago • 2 comments

Amsterdam researchers refute claims that Long COVID muscle issues are just deconditioning. Their study shows clear physiological differences, including mitochondrial dysfunction, in patients with post-exertional malaise. www.nature.com/articles/s41...

submitted 19 days ago • 2 comments

🚨 “COVID-19 May Enduringly Impact Cognitive Performance and Brain Haemodynamics in Undergraduate Students” h/t @kathrynas.bsky.social on BlueSky https://www.sciencedirect.com/science/article/pii/S0889159124007311 #COVID #COVIDIsNotOver #COVIDIsNotMild #WearAMask #LongCOVID #ChronicIllness […]

submitted 20 days ago • 0 comments

Fibrin-targeting immunotherapy may represent a therapeutic intervention for patients with Long COVID. Published: 28 August 2024 Fibrin drives thromboinflammation and neuropathology in COVID-19 www.nature.com/articles/s41... Jae Kyu Ryu, Zhaoqi Yan, …Katerina Akassoglou Show authors

submitted 22 days ago • 2 comments

"We must recognise the collective wisdom of those with lived experience of #longCovid. #Scientific and #medical advances since 2020 have shown us that #LongCovid encompasses a broad constellation of symptoms and disease, and while we can ..." www.bmj.com/content/388/...

submitted 22 days ago • 0 comments

Long COVID alone has cost more than those savings, affects an estimated 40-50 million Americans at the time of this article, and minimum thousands more people each week. That's one disease. One single disease. pubmed.ncbi.nlm.nih.gov/39842946/ @resist.bot is a very easy way to contact your reps 😷

submitted 22 days ago • 0 comments

2/5/25, “Long-COVID incidence proportion in adults and children between 2020 and 2024” “on behalf of the RECOVER EHR Cohort” academic.oup.com/cid/advance-...

submitted 24 days ago • 2 comments

It turns out that ignoring a pandemic doesn't make it go away. Long Covid incidence is actually rising over time with the later Omicron variants.

submitted 24 days ago • 1 comment

#MeetThePapers Published today! Neurological sequelae of long COVID: a comprehensive review of diagnostic imaging, underlying mechanisms, and potential therapeutics www.frontiersin.org/journals/neu... We wrote the most comprehensive review of long COVID brain so far! #NIHImpact #AcademicSky

submitted 23 days ago • 1 comment

“Now in its 6th year of circulation, SARS-CoV-2)—the virus that causes #COVID-19—continues to evolve and infect people, leading to serious disease, #LongCovid) & death” 👇🏼 Forgetting the evidence only makes us more vulnerable. Let’s not. #health www.science.org/doi/10.1126/...

submitted 26 days ago • 0 comments

In 2023, 1.4% of US kids had long COVID, with 0.4% still affected. Older kids and those from lower-income families were most impacted. 80% had activity limitations. jamanetwork.com/journals/jam...

submitted 27 days ago • 1 comment

There is so much great work coming out every week on #longCOVID. This study shows increased levels of b amyloid pathology. Increases in these biomarkers in turn were associated with grey matter volume reduction and functional imaging patterns similar to AD progression. www.nature.com/articles/s41...

submitted 30 days ago • 1 comment

"Four lessons #COVID taught us about the #immune system ... people with #longCOVID, says Iwasaki. How best to treat long COVID is just one of many unanswered mysteries in the wake of the COVID-19 #pandemic." www.nature.com/articles/d41...

submitted 30 days ago • 1 comment

Five years after COVID-19, kids face more infections, long COVID, and mental health struggles. Experts warn that without more healthcare funding, the impact could last for generations. www.sciencedirect.com/science/arti...

submitted 30 days ago • 0 comments

A meta-analysis of 51 studies finds that adults with asthma face a 41% higher risk of long COVID, while those with COPD see a 32% increase. Asthma is also linked to a greater likelihood of long COVID-related fatigue. bmjopenrespres.bmj.com/content/12/1...

submitted 30 days ago • 4 comments

Medscape: “Paxlovid: Worth a Long Look for Easing Long COVID” “Putrino thinks that we should be using monoclonal antibodies that are capable of reversing severe long COVID in more patients.” www.medscape.com/viewarticle/...

submitted 30 days ago • 2 comments

#Disability "Long Covid symptoms include a postexertional exhaustion reminiscent of other postviral illnesses, such as myalgic encephalomyelitis– chronic fatigue syndrome (MECFS) with suspected latent viral reactivation" www.science.org/doi/10.1126/...

submitted 30 days ago • 0 comments

Mild #SARSCoV2 infection results in long-lasting microbiota instability #MECFS #LongCovid journals.asm.org/doi/10.1128/...

submitted 30 days ago • 1 comment

New US poster abstract from a long-term ME/CFS expert, John Chia: Efficacy Of SARS–CoV-2 Specific Antiviral Therapy for Enteroviral Myalgic Encephalomyelitis/ChronicFatigue Syndrome academic.oup.com/ofid/article... #MEcfs #CFS

submitted 29 days ago • 2 comments

It is so cringe-worthy, trying to pretend to be correct and relevant while spreading so much disinformation! Now pretending again that SARS-CoV-2 damages "the immune system" by extrapolating specific LongCovid cohorts. It is so bad to see people falling for this. Why is this wrong again?

submitted 31 days ago • 4 comments

A little good news for long covid sufferers.

submitted 36 days ago • 0 comments

Meanwhile: www.bmj.com/content/382/... Long covid: nearly half of doctors affected can no longer work full time ... Wear a damn mask. #MedSky

submitted 36 days ago • 0 comments

everyone talks about how the CDC changes the colors on the COVID wastewater map but the fact that they re-baseline every 6 months is far, far more egregious

submitted 149 days ago • 1 comment

CDC is changing the baseline for wastewater levels, so here's where you can get the raw data: data.wastewaterscan.org This is the CDC's source, so very reliable and you can also customize the time-period using this tool.😄

submitted 43 days ago • 0 comments

CDC is adjusting their wastewater baseline calculation to not show that covid is infecting more people in the period between waves. By using 12 months of data instead of 18 like for flu/RSV, it disguises increases in the average over time.🤨 Up side is a JN.1 type variant will stand out more.😅

submitted 43 days ago • 3 comments

I see many people asking, "Has anyone tried XYZ for LC (or ME/CFS)? You can view patient-reported treatment outcomes for ME/CFS & Long COVID in this spreadsheet. Scroll to the right to see treatment results for ME/CFS (Columns S - AA) or Long COVID (Columns AB - AJ). docs.google.com/spreadsheets...

submitted 41 days ago • 29 comments

A review of 31 studies finds Long COVID impairs memory, attention, and inhibition, linked to disruptions in the brain’s frontal and cerebellar regions. www.cell.com/heliyon/full...

submitted 41 days ago • 7 comments

New from Spain: SARS-CoV-2 Viral Load and Cytokine Dynamics Profile as Early Signatures of Long COVID Condition in Hospitalized Individuals onlinelibrary.wiley.com/doi/10.1111/... Image is from latest Science for ME weekly update #LongCovid #PASC

submitted 41 days ago • 0 comments

Two studies reveal lasting neurological impacts of COVID-19 Brainstem changes persist months after recovery, tied to inflammation Long COVID disproportionately harms young adults, affecting cognition and quality of life, especially for the workforce www.nature.com/articles/s41...

submitted 44 days ago • 0 comments

Medical News: “Patients who have had multiple COVID infections appear prone to contracting long COVID” The findings are published early online in the February edition of The Lancet Regional Health—Americas medicalxpress.com/news/2025-01...

submitted 44 days ago • 1 comment

In case anyone is still on the fence about #LongCovid being real... nearly 18k publications in the NIH's LitCovid database are about #LongCovid (in 5 years!). Source: www.ncbi.nlm.nih.gov/research/cor...

submitted 44 days ago • 2 comments