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tyewdell.bsky.social
B cells | plasma cells |autoimmunity | MS | IBD | lupus | immune memory | tiki taka | geggenpressing | Group Leader/Principal Scientist at Genentech https://www.gene.com/scientists/our-scientists/teddy-yewdell
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Excited to share our study describing a role for a subset of Thetis cells, TC IV, in tolerance to food antigens. A team effort led by Vanja Cabric and Yollanda Parisotto www.science.org/doi/10.1126/...

“We all said to each other, ‘This is the most significant thing we have ever done.” An amazing story, and yet one that does not happen without federally funded basic research www.nytimes.com/2025/05/15/h...

Andor is really freaking me out - impeccable timing!

'I did not complete a customs declaration for frog embryos (...) this would normally result in a warning or fine. Instead, my visa was revoked & I was sent to a detention center in Louisiana, where I have spent the past 3 months with roughly 100 other women. We share one room w dormitory-style beds'

Just deranged. This was a *solved* problem.

This is what scientific leadership and courage looks like: www.harvard.edu

Published an op-ed for @cnn.com: “Nobel laureate: I owe America my success. Today, its scientific future is in danger.” A personal reflection on what’s at stake as science funding gets slashed. I’d be grateful if you could amplify both in and beyond the science world. www.cnn.com/2025/04/09/h...

Love this, and also kinda sad we are done with strollers… I’m not crying, you’re crying!!! www.nytimes.com/2025/04/12/s...

www.nytimes.com/2025/04/03/o... Really important piece to share widely. Too many Americans don’t know how severe a threat this Administration poses to our scientific infrastructure, global leadership, and health security

Great to have our paper out in @pnas.org showing that lung B cells in ectopic germinal centers undergo affinity maturation. @smguillaume.bsky.social @wsfoster.bsky.social @sanmarti92.bsky.social @emae-watson.bsky.social Silvia Innocentin, Grant Kennedy & Alice Denton. doi.org/10.1073/pnas...

I remember seejng this as a preprint a while ago, incredibly clever analysis, and profound inplications. So much biology to discover in the neuroimmune domain!! www.nature.com/articles/s41...

Call to arms by @lisamjarvis.bsky.social for biopharma to mobilize in support of the engines that power them - federally supported biomedical research and drug evaluation

“Internet, vaccines, anything you can think of, were originally developed by publicly funded research programmes, and nobody at the time could have foreseen what would come out of them.” @marialep.bsky.social www.irishtimes.com/science/2025...

"This is not a left or right moment. It is a right or wrong moment." -- Senator Cory Booker, today

Thank you, Cory Booker for defending scientific research. Speaking out against the mindless, tragic loss of economic benefit, our global scientific competitive edge and hope for so many families in health crises so clearly after standing there for 24 hrs is remarkable.

People/organizations with means and a vision for the future of biomedical science - we need an “Arc Institute” equivalent in the DMV area to sponge up all the incredible talent, opportunity of a lifetime for a visionary entrepreneur, I will help! @mcuban.bsky.social

"This will go down as one of the darkest days in modern scientific history." Story on the decimation of NIH by @maxkozlov.bsky.social www.nature.com/articles/d41...?

Go, @booker.senate.gov , Go!!! We need more like this from our leaders NOW.

Too good! www.threads.net/@dillongeyse...

1. For the past thirty years I've had the best job in the world. 
I've had the opportunity to follow my curiosity; explore the workings of nature and society; mentor students and junior colleagues in the same process; and teach generations of students about it all.

‘If a VC firm measured efficiency purely by how little money it spent, rather than by the returns it generated, it wouldn’t last long. We invest in scientific research because we want returns — in knowledge, in lifesaving drugs, in technological capability.’ www.nytimes.com/2025/03/19/o...

Pls read and share with family members. Thank you AAI for speaking up!!

Well worth a read. Not because of the content - it's total horseshit - but because it's a prime example of what happens when you mix anti-science, conspiracism, arrogance, and a total lack of expertise. Maybe one day NYT OpEds will engage with the actual science 🤷‍♂️. www.nytimes.com/2025/03/16/o...

Cartoon by @paulnoth.bsky.social

Interested in germinal center regulation? Should we coddle our immune system? Two more weeks to apply! 3 year funding

Very excited our work out in @jem.org “Transient inhibition of type I interferon enhances CD8+ T cell stemness and vaccine protection” @wehi-research.bsky.social led by talented (and determined) PhD student @benjbroom.bsky.social Thread below.

A reminder that mRNA vaccines are among the greatest scientific and medical breakthroughs ever, with almost unlimited potential against infectious diseases and many different types of cancer.

One of the most powerful moments of the day came from Emily Whitehead who told the story of how she was the first pediatric patient to receive CAR T-cell therapy for her leukemia at age 5: “I stand up for science because science saved my life. And that’s a fact.” @standupforscience.bsky.social