Holy SHIT. Okay, this needs an "in mice" caveat, but the tactic they took means it's less of a caveat than usual and also HOLY FUCKING SHIT
Reposted from
Ryan
Scientists have created an actual treatment for prions, the cause of Creutzfeldt–Jakob disease in humans, chronic wasting disease in deer, & mad cow disease.
"Brainwide silencing of prion protein by AAV-mediated delivery of an engineered compact epigenetic editor". #ShareGoodNewsToo
"Brainwide silencing of prion protein by AAV-mediated delivery of an engineered compact epigenetic editor". #ShareGoodNewsToo
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And given the severity of the disease in question, you can tolerate a lot of invasiveness of treatment here.
If it works in humans, it's Nobel prize winning stuff.
Science and medical research is awesome.
goddamn this looks PROMISING
I hate prions so fucking much, it's unreal.
"CHARM represents a therapeutic modality that could be applied to a range of other diseases caused by the toxic buildup of unwanted proteins."
That seems to me like a translation of "We think there's a chance this might work on Alzheimers, so that's worth investigating," and I am HERE FOR IT
prions have always been a total death sentence, this is wild
We are in a biomedical revolution. All sorts of unexpected good things are going to happen.
sure it might not pan out! but It's INTERESTING.
The damned misfolded demon springs are finally *vulnerable*.
Human would be amazing, but bovine wouldn't be nothing either.