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epididymosome.bsky.social
Magic Science Dude, Round 4. Uncouth, spitting out the sunroof through my missing tooth. Chromatin structure and function, paternal effect paradigms, reproductive biology and lil embryos.
105 posts 1,768 followers 1,877 following
Prolific Poster

George Lucas should've added five or six more suns to the Tattooine Sunset for the Special Edition

This looks like an exciting paper! www.science.org/doi/10.1126/...

For decades, government funding “has positioned the United States as a global leader” in science, says scientist Tom Maniatis of @zuckermanbrain.bsky.social and the New York Genome Center. He highlights how a new #NIH policy cutting money for research “jeopardizes” this, in Cell tinyurl.com/ubw6uphe

Someone made a Wiley E. Coyote style painted wall to see if Tesla’s autopilot would detect it and well…

www.nature.com/articles/s41...

einstein sent this to curie in 1911 when she was being harassed by tabloids. it contains everything you’d want in such a letter: (1) your haters are trash (2) you’re a baller, a true queen (3) i have determined the statistical law of motion of the diatomic molecule in planck’s radiation field 🧪⚛️

1/ Transposable elements are often called "jumping genes" because they mobilize within genomes. 🧬 But did you know they can also jump 𝘣𝘦𝘵𝘸𝘦𝘦𝘯 cells? 🤯 Our new study reveals how retrotransposons invade the germline directly from somatic cells. www.biorxiv.org/content/10.1... A short thread 🧵👇

Whispering to myself over and over in the grocery store: The pickleman isn’t real, he can’t hurt you. The pickleman isn’t real, he can’t hurt you.

Every breed has its own melting point

🧪 Finally!!! A single-cell atlas of the mouse seminal vesicle!!! (seriously though, it just might be the last major mammalian organ to undergo single cell sequencing). Check it out! pubmed.ncbi.nlm.nih.gov/40036847/#fu... @arturmansl.bsky.social @anashin.bsky.social @epididymosome.bsky.social

he was afraid of needles! absolute legend www.npr.org/2025/03/03/n...

This is really good, from my department neighbor and buddy, and awesome dude, Sean Ryder

#Transposons are parasitic genetic elements that act as raw material for evolution of new functions. @briankelch.bsky.social &co show that the capsid of the #virus-derived retrotransposon Copia mediates synaptic plasticity at the #Drosophila neuromuscular junction 🧪 @plosbiology.org plos.io/3X71IDa

No one has ever fumbled the bag harder than the app that had a monopoly on the video conferencing and then got cooked by Zoom during the pandemic. In 2019, Skype had 300 million active monthly users.

UPDATE: HE RETURNED IT

Excited to share the work of Jonathan Perr where he uncovered a surprisingly common feature of cell surfaces - the presentation and clustering of RNA binding proteins with #glycoRNA. Critically support by #NIH @cp-cell.bsky.social www.cell.com/cell/abstrac...

no meat

RNA xkcd.com/3056

Attempting to describe the current American political situation is a grimly laughable mindfck because it triggers all the mental alarm bells that are meant to help you avoid sounding “unhinged” or “dramatic” in polite conversation when really we’re just in an objectively insane situation

Happy 10th birthday to the Ea-Nasir complaint tablet meme! A glorious decade of memes, mashups, merchandise, erotic fanfic, real-life copper fraud, and pilgrimages to the British Museum. Thread 🧵:

Personally, I would argue that something that feels nothing looking at something that means nothing tells us not much of use. Unless this is a meta joke about constructing insights from randomness? In which case, fair play

🪲🌲Hi all! I'm Lain, a Michigan-based dark nature artist. I love foraging and painting. Since platforms are shifting right now, I'd love to meet some cool folks on Bluesky who also like weird nature stuff too 🪲🌲

So close! DNA is the DNA of life.

journals.plos.org/plosbiology/...

Legendary hater Charles Darwin

WSJ sub: “Indian Partition went smoothly enough, right? Will try to remember to check this before publishing.”

around this time every night the old rocking chair in the basement starts rocking by itself I am irresistibly drawn to it as soon as I sit down in it I am overcome with a heavy dreamless sleep and the next morning another person from town has gone missing

pulled my back so bad that I told my family I might need a wheelchair like Professor X, and my son said “yeah more like Professor XXL” and goddammit I don’t deserve this abuse

attempting to describe the vibes of the moment. have yet to do better than: "imagine watching a documentary reenacting the burning of the Library of Alexandria set to the soundtrack of 'Yakety Sax'"

Do not cry www.wfla.com/news/florida...

Genome architecture folks, this perspective is really worth your time www.cell.com/molecular-ce...

The Institute mourns the loss of R. Scott Hawley, PhD. A brilliant scientist, cherished colleague, and true mentor. Scott's contributions to our understanding of genetics and passion for training the next generation of scientists will forever be remembered. bit.ly/3WPqqYG

I see some suggestions, in the reporting regarding the OMB impoundment order, that a mere delay in spending appropriated funds is legal. But that's not really true. The delay OMB has ordered specifically contradicts the Impoundment Control Act. A thread.

I wrote something in cursive and a 20 year old told me the they didn't speak French.

"Aye, the sirens," says the lighthouse keeper, picking a bit of tobacco from his beard. "Some nights, when the wind is just so, I swear I can hear 'em singing." "What do they sing?" I prod him. A faraway look in his eyes, he says in a voice barely above a whisper, "Tubthumping."

Happy 5th "Large boulder the size of a small boulder" anniversary! #Geology ⚒️

An absolutely fascinating video about the surprising multi-level nature of a Chinese city - it’s like a Escher drawing in concrete, steel and glass

M: that’s O: not R: how O: acronyms N: work

my best guess is a vampire fell asleep on it last night

Videogame: The world is ending in dragonfire, you have 24 hours to save us or we all die Videogame: But first I need 20 flowers

What is the multiscale structure of chromatin condensates? How does it shape thermodynamic and material properties? We address this at near-atomistic resolution🔥🔥🔥 using cryoET (Rosen & Villa labs, led by H Zhou), a new multiscale model (K Russell) and cryoET-guided sims (J Huertas & J Maristany)

the muppets on the cover of national geographic: thread

Study sections are the review panels that allocate NIH research grants. They bring in experts from around the country and have to be scheduled many months in advance; they provide the funds that keep the nation's biomedical research going. It's hard to overstate the disruption this causes.

Love this, it represents the next (still coarse) step towards reconstituting arbitrary chromatin polymers (Nuc1:K14ac/K27me3; Nuc2:K16acK4me3;etc.) for folding and transcription studies

Are you using 5xFAD mice to study Alzheimer’s disease? Our work out today @cp-neuron.bsky.social may be relevant to you 🐁🧠 Age and sex are known to influence Aβ plaque burden in these mice. Here, we found that the transgene parentage is another strong determinant. Thread below: (1/11)

Mild January in Porkkalanniemi 📷Canon T70 + New FD 28/8 🎞️Fujifilm Acros II #Fujifilm #filmphotography

yesterday I assembled an entire woodshed without even needing to consult the instructions Today I will dismantle an entire woodshed Tomorrow I will re-assemble an entire woodshed, this time while consulting the instructions